Cancer BiologybioRxivPreprint
ecDNA-driven oncogene super-expressors shape immunoevasive tumor microenvironment
Kailiang Qiao, Qing‐Lin Yang, Tuo Li…·Sihan Wu
This study shows ecDNA-driven oncogene super-expressors create an immunoevasive tumor microenvironment in PDAC by promoting myCAF expansion and suppressing T cell infiltration.
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