Author

Travis E. Hartman

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-3926-6928Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Justin R. CrossiD· 2 shared Adrián JinichiD· 1 shared Arshia Arasappan· 1 shared Atul PradhaniD· 1 shared Carl NathaniD· 1 shared Charles Kyriakos VorkasiD· 1 shared Hui LiuiD· 1 shared Jahan A. RahmaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

Justin R. CrossORCID

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3 papers

Recent·Most cited

Loss of riboflavin biosynthesis leads to accumulation of select aromatic amino acids and loss of infectivity in Mycobacterium tuberculosis

Neetika Jaisinghani, Arshia Arasappan, Atul Pradhan, Rimanpreet Kaur, Kelin Li, Jeffrey Aubé, Justin R. Cross, Ruben J. Jesus Faustino Ramos, Travis E. Hartman, Mary Lou Previti, Charles Kyriakos Vorkas, Jessica C. Seeliger

This paper shows that disrupting riboflavin biosynthesis in Mycobacterium tuberculosis leads to metabolic changes and loss of infectivity in mice.

bioRxiv · Aug 5, 2026 · PreprintMicrobiology

MEK-dependent bioenergetic demand drives terminal CD8+ T cell exhaustion

Tanya Mitra, Jahan A. Rahman, Madeline A. Hwee, Yan-Ting Chen, Ruben Jose Jesus Faustino Ramos, Hui Liu, Travis E. Hartman, Justin R. Cross, Miguel de Jesus, Morgan Huse, Valerie A. Longo, PAT B. ZANZONICO, Santosha Adipudi Vardhana

This study shows that MEK inhibition reduces mitochondrial dysfunction and terminal CD8+ T cell exhaustion by decreasing nutrient uptake and RNA polymerase II activity.

Immunity · Jul 13, 2026Peer-reviewedImmunology

Candidate transmission survival genome of Mycobacterium tuberculosis

Saurabh Mishra, Prabhat Ranjan Singh, Xiaoyi Hu, Landys A. Lopez Quezada, Adrián Jinich, Robin Jahn, Luc Geurts, Naijian Shen, Michael A. DeJesus, Travis E. Hartman, Kyu Young Rhee, Matthew Zimmerman, Veronique Anne Dartois, R. Mark Jones, Xiuju Jiang, , Carl Nathan

This study identifies a candidate transmission survival genome of Mycobacterium tuberculosis by exposing it to model aerosol fluid and analyzing gene contributions to survival during transmission.

Proceedings of the National Academy of Sciences · Mar 7, 2025Peer-reviewedMicrobiology