Irina Balaguer Balsells

This study creates a single-nucleus multiomic and spatial atlas of human spermatogenesis, linking gene regulatory networks to infertility-associated genetic variation and disease perturbations.

The paper identifies temporally distinct CDX-driven regionalisation events that preconfigure vagal and trunk neural crest identities in mouse embryos.

This study reveals a unique 3D genome architecture in premeiotic gonadal germ cells, linked to epigenetic reprogramming and loss of TADs, alongside DNA demethylation.

This study identifies Y-chromosome gene functions in mouse spermatogenesis by generating Y-deletion models and analyzing gene effects on fertility.