Jingting Yu

The paper identifies YAP1 as a non-canonical effector of RA signaling essential for atrial lineage commitment in cardiac progenitor cells.

This study identifies how RORγt mutations affect gene activation by altering chromatin binding modes, explaining context-dependent autoimmunity and host defense outcomes.

This study shows that PPARδ limits CIITA-MHC II expression in Tregs, reducing their immunosuppressive function and enhancing anti-tumor responses.

The paper integrates Hi-C and eQTL data from multiple human tissues and cell lines to show eQTLs and their target genes are often in the same topologically associating domains and have higher chromatin interaction frequency.