Author

Harold M. McNamara

Princeton UniversityORCID 0009-0006-6593-6477Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Adam E. CoheniD· 1 shared Alexander F. SchieriD· 1 shared Alexandra E. WehmeyeriD· 1 shared Alexandre MayraniD· 1 shared Alfonso Martínez AriasiD· 1 shared Alison GuyeriD· 1 shared André DiasiD· 1 shared Bill JiaiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperDevelopmental Biology

Adam E. CohenORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedMar 27, 2025

Optogenetic control of Nodal signaling patterns

Harold M. McNamara, Bill Jia, Alison Guyer…·Nathan D. Lord

This study develops optogenetic tools to control Nodal signaling patterns in zebrafish embryos, enabling precise spatial manipulation of signaling activity and rescue of developmental defects.

16 citations

zebrafishexperimental assay

𝕏 PostBluesky

Developmental BiologybioRxivPreprintJan 11, 2025

Opposing Nodal and Wnt signalling activities govern the emergence of the mammalian body plan

André Dias, Pau Pascual-Mas, Gaëlle Robertson…·Alfonso Martínez Arias

This study shows that Nodal and Wnt signalling act antagonistically during mammalian gastrulation, with Nodal promoting anterior structures and Wnt driving posterior development.

19 citations

mousestatistical model

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Developmental BiologybioRxivPreprintJun 2, 2023

Recording morphogen signals reveals origins of gastruloid symmetry breaking

Harold M. McNamara, Sabrina C. Solley, Britt Adamson…·Jared E. Toettcher

The paper shows that Wnt signaling heterogeneity predicts cell position in gastruloids, revealing symmetry breaking through signaling and cell movement.

19 citations

humanscRNA-seq

𝕏 PostBluesky