Author

Yizhi Jiang

Harvard UniversityORCID 0000-0001-9016-1104Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

J. Wade HarperiD· 3 shared João A. PauloiD· 3 shared Felix KrausiD· 2 shared Florian WilflingiD· 2 shared Steven P. GygiiD· 2 shared Anna BieberiD· 1 shared Annie JeniD· 1 shared Benton J. AndersoniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

J. Wade HarperORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A human lysosomal storage disorder toolkit for decoding proteome landscapes in cortical and dopaminergic-like induced neurons

Felix Kraus, Yuchen He, Yizhi Jiang, Delong Li, Yohannes Abere Ambaw, Federico M. Gasparoli, João A. Paulo, Tobias C. Walther, Robert V. Farese, Steven P. Gygi, Florian Wilfling, J. Wade Harper

The paper develops a human stem cell toolkit for studying lysosomal storage disorders by generating proteomic data from induced cortical and dopaminergic-like neurons.

Proceedings of the National Academy of Sciences · Jul 1, 2026Peer-reviewedCell Biology

EndoMAPV1, a Structural Protein Complex Landscape of Human Endosomes

Miguel A. Gonzalez‐Lozano, Ernst W. Schmid, Enya Miguel Whelan, Yizhi Jiang, João A. Paulo, Johannes C. Walter, J. Wade Harper

The paper creates a structural interactome of human endosomes using cross-linking, mass spectrometry, and AlphaFold, identifying structural models for endosomal protein complexes.

Nature · May 28, 2025Peer-reviewedCell Biology

Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST

Felix Kraus, Yuchen He, Sharan Swarup, Katherine A. Overmyer, Yizhi Jiang, Johann Brenner, Cristina Capitanio, Anna Bieber, Annie Jen, Nicole M. Nightingale, Benton J. Anderson, Chan Lee, João A. Paulo, Ian R.L. Smith, Jürgen M. Plitzko, , J. Wade Harper

This study uses nMOST to profile proteo-lipidomics in lysosomal storage disease mutants, revealing autophagy defects and mitochondrial dysfunction.

Science Advances · Jan 22, 2025Peer-reviewedCell Biology