Zepu Miao

Multidimensional telomere diversity and inheritance at individual and population scales

This paper introduces TeloXplorer, a framework for analyzing telomere features in long-read data, showing how telomere diversity is inherited across species and populations.

The genome of the early diverged amphioxus, Asymmetron lucayanum, illuminates the evolution of genome architecture and gene repertoires in cephalochordates

This study presents a chromosome-anchored genome assembly of Asymmetron lucayanum, revealing genome architecture and gene evolution in cephalochordates.

VRPG: an interactive visualization framework for reference-projected pangenome graph

VRPG provides an interactive visualization framework for pangenome graphs, enabling exploration, annotation, and comparison of genomic variation across species.

GetPrimers: a generalized PCR-based genetic targeting primer designer enabling easy and standardized targeted gene modification across multiple systems

GetPrimers is a computational tool for designing PCR-based genetic targeting primers, validated across multiple organisms and experimental setups.

142 telomere-to-telomere assemblies reveal the genome structural landscape in Saccharomyces cerevisiae

This paper presents 142 high-quality yeast genomes to improve pangenome understanding, identifying structural variants and complex genomic regions.

Fine mapping of goat polledness variant in six Chinese native breeds

The paper identifies a structural variant associated with goat polledness through GWAS and CNV analysis, linking it to the ERG gene and providing insights into its molecular mechanisms.

Whole-genome sequencing of Chinese native goat offers biological insights into cashmere fiber formation

The paper identifies a 582bp deletion upstream of LHX2 associated with cashmere production in goats through whole-genome sequencing and functional assays.