Yi Yang

The paper quantifies oxygen gradients in the intestine and recreates them ex vivo to study hypoxia's role in epithelial organization.

The paper demonstrates multiplex base editing to convert TAG to TAA codons in 33 essential human genes and introduces a computational tool for recoding.

This study shows that regulatory T-cells are essential for neonatal heart regeneration, as their depletion impairs cardiac repair and increases fibrosis.