Yiran Tao

SOFT METROPOLIS-HASTINGS CORRECTION FOR GENERATIVE MODEL SAMPLING

The paper introduces a soft Metropolis-Hastings correction for molecular diffusion models to improve chemical validity and structural stability in molecule generation.

Learning from B Cell Evolution: Adaptive Multi-Expert Diffusion for AntibodyDesign via Online Optimization

This paper introduces an adaptive diffusion model for antibody design inspired by B cell evolution, showing improved optimization across diverse targets.

Determine Interaction Affinity Changes of the SUMO E1 Activating Enzymes During SUMO Activation using Quantitative FRET technology

The paper determines the interaction affinity and kinetics of the Aos1-Uba2 heterodimer during SUMO activation using qFRET and SPR, showing increased stability with SUMO and ATP binding.

Cross-scale visualization of RNA dynamics in whole plants using an RNA-triggered reporting system

This paper develops an RNA-triggered fluorescence reporter system for real-time visualization of RNA dynamics across spatial scales in whole plants.

Expanding GABAergic Neuronal Diversity in PSC-Derived Disease Models

This study develops a method to generate diverse GABAergic neurons from PSCs using TFs and signaling inhibition, showing distinct subtype compositions and disease relevance.