Benedikt N. Eisinger

The paper uses a multiplexed single-cell transcriptomic screen to study how morphogen cues affect regional specification in human neural organoids, finding that timing, concentration, and combination of morphogens strongly influence cell type and regional composition.

The paper programs human neuron subtypes using combinatorial patterning and scRNA-seq to identify diverse neuron types and their developmental signaling networks.

The paper reconstructs epigenomic trajectories in human neural organoids from pluripotency to terminal cell states using single-cell histone modification profiling.