Samuel Protais Nyandwi

This paper introduces TeACAT, a method to track newly synthesized proteins in mice by incorporating a non-canonical amino acid, enabling visualization and quantification with minimal perturbation.

The paper investigates a disease-causing mutation in IARS1 that affects protein complex formation and the integrated stress response, leading to altered cellular stress responses.

This study shows that RARS1's integration into the multisynthetase complex is essential for normal brain development in mice, as its exclusion leads to developmental defects and gene dysregulation.