Author

Michelle L. Kirtley

The University of Texas MD Anderson Cancer CenterORCID 0009-0009-1960-3032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Kent A. Arian· 3 shared Raghu KalluriiD· 3 shared Bingrui LiiD· 2 shared Hikaru SugimotoiD· 2 shared Kathleen M. McAndrewsiD· 2 shared Krishnan K. MahadevaniD· 2 shared Sami J. MorseiD· 2 shared Shreyasee V. Kumbhar· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

Kent A. Arian

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 20, 2026

TGF-β2-induced Snail-mediated EndMT signaling relies on both Smad-dependent and independent pathways

Valerie S. LeBleu, Bingrui Li, Anaïs M Comptdaer…·Raghu Kalluri

The paper reproduces and validates a previously reported model of TGF-β2-induced EndMT through Smad-dependent and independent pathways across multiple studies and laboratories.

DOI 10.64898/2026.08.17.745236

experimental assaybenchmarking

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Cancer BiologybioRxivPreprintJan 29, 2025

CDK8 remodels the tumor microenvironment to resist the therapeutic efficacy of targeted KRASG12D inhibition in pancreatic ductal adenocarcinoma

Kathleen M. McAndrews, Krishnan K. Mahadevan, Bingrui Li…·Raghu Kalluri

This study investigates how CDK8 remodels the tumor microenvironment to resist KRASG12D inhibition in PDAC, showing that targeting CDK8 can overcome resistance and improve survival.

4 citations

humanspatial transcriptomics

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ImmunologyJournal of Controlled ReleasePeer-reviewedAug 30, 2024

Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity

Xin Luo, Kathleen M. McAndrews, Kent A. Arian…·Raghu Kalluri

This paper develops an engineered extracellular vesicles-based vaccine platform for combined mRNA and protein delivery, showing tumor regression and immune responses in preclinical models.

30 citations

mousenon-human primate

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