Author

Nathaniel C. Gualberto

Washington University in St. LouisORCID 0009-0009-2697-5862Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Edward D. B. LopattoiD· 2 shared Jerome S. PinkneriD· 2 shared Karen DodsoniD· 2 shared Scott J. HultgreniD· 2 shared Aaron J. SchmitziD· 1 shared Ali H. EllebedyiD· 1 shared Andrew L. KauiD· 1 shared Denise A. SanickiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Edward D. B. LopattoORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MicrobiologybioRxivPreprintDec 3, 2025

The lac operon in uropathogenic Escherichia coli enhances intracellular growth by enabling host glycan utilization

Jesús Bazán Villicaña, Devina Puri, Taylor M. Nye…·Scott J. Hultgren

This study shows that the lac operon in uropathogenic E. coli enables host glycan utilization, enhancing intracellular growth and infection dissemination.

DOI 10.64898/2025.12.03.691977

E. coliproteomics

𝕏 PostBluesky

MicrobiologyScience AdvancesPeer-reviewedJun 20, 2025

Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI

Edward D. B. Lopatto, Jesús M. Santiago-Borges, Denise A. Sanick…·Scott J. Hultgren

This study identifies two monoclonal antibodies against FimH adhesin that protect mice from E. coli UTI by sterically blocking FimH function, offering an antibiotic-sparing treatment strategy.

22 citationstop 1%

mouseexperimental assay

𝕏 PostBluesky