Author

Andrew L. Kau

Washington University in St. LouisORCID 0000-0002-9386-3766Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Karen DodsoniD· 2 shared Philippe N. AzimzadehiD· 2 shared Scott J. HultgreniD· 2 shared Aaron J. SchmitziD· 1 shared Abigail L. MansoniD· 1 shared Ali H. EllebedyiD· 1 shared Andreas GnirkeiD· 1 shared Ariel J. Hernandez-LeyvaiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

Karen DodsonORCID

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Author profile →

3 papers

Recent·Most cited

Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI

Edward D. B. Lopatto, Jesús M. Santiago-Borges, Denise A. Sanick, Sameer Kumar Malladi, Philippe N. Azimzadeh, Morgan R. Timm, Isabella F. Fox, Aaron J. Schmitz, Jackson S. Turner, Shaza M. Sayed Ahmed, Lillian Ortinau, Nathaniel C. Gualberto, Jerome S. Pinkner, Karen Dodson, Ali H. Ellebedy, , Scott J. Hultgren

This study identifies two monoclonal antibodies against FimH adhesin that protect mice from E. coli UTI by sterically blocking FimH function, offering an antibiotic-sparing treatment strategy.

Science Advances · Jun 20, 2025Peer-reviewedMicrobiology

Distinct Escherichia coli transcriptional profiles in the guts of recurrent UTI sufferers revealed by pangenome hybrid selection

M. G. Young, Timothy J. Straub, Colin J. Worby, Hayden C. Metsky, Andreas Gnirke, Ryan A. Bronson, Lucas R. van Dijk, Christopher A. Desjardins, Christian B. Matranga, James Qu, Jesús Bazán Villicaña, Philippe N. Azimzadeh, Andrew L. Kau, Karen Dodson, Henry L. Schreiber, , Ashlee M. Earl

This study identifies distinct E. coli transcriptional profiles in the guts of recurrent UTI sufferers using a novel pangenome hybrid selection method.

Nature Communications · Nov 2, 2024Peer-reviewedMicrobiology

The gut metagenome harbors metabolic and antibiotic resistance signatures of moderate-to-severe asthma

Naomi G. Wilson, Ariel J. Hernandez-Leyva, Drew J. Schwartz, Leonard B. Bacharier, Andrew L. Kau

This study identifies functional changes in the gut metagenome of individuals with moderate-to-severe asthma, including LCFA metabolism and antibiotic resistance gene enrichment.

FEMS Microbes · Jan 1, 2024Peer-reviewedGenomics