Monica Ortelli

This study introduces HIDEN-SEQ, a transposon-insertion sequencing method for phages, to systematically map gene essentiality and uncover previously unknown viral anti-defense factors.

This study uses CRISPRi to identify genetic factors affecting E. coli adaptation across diets, inflammation, and strains in a mouse model.

This study uses CRISPRi to identify metabolic vulnerabilities of UPEC in urine, highlighting ALS II as a druggable target.

This study identifies YopJ homologs in Bartonella as T4SS effectors, showing they evolved from an ancestral T4SS effector through acquisition of a T3SS translocation signal.