Author
Memorial Sloan Kettering Cancer CenterORCID 0009-0009-3267-8450Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Arpita Chakravarti, Yi Wu, Alexander Maxwell Burroughs…·Dinshaw J. Patel
The paper identifies Pucsar, a bacterial antiphage system that uses 3,5-cGMP generated by a cyclase to activate TIR effectors through a stepwise filament assembly process.
Zhiying Zhang, Yi Wu, Yan‐Jiun Lee…·Franklin L. Nóbrega
The paper identifies a methylome-derived m6-dAMP trigger that forms an immune filament in E. coli to deplete dNTPs and abort phage infection.
Matthieu Haudiquet, Arpita Chakravarti, Zhiying Zhang…·Dinshaw J. Patel
This study reveals the structural basis and evolutionary origin of the Lamassu bacterial immune system, showing its adaptation from DNA repair machinery to detect and respond to viral replication.