Author

Sofia Lemak

University of TorontoORCID 0009-0009-3479-1609Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:structural biology· 2 Organism:virus· 1

Frequent Co-Authors

Alexei V. SavchenkoiD· 2 shared P. J. StogiosiD· 2 shared Deepak T. PateliD· 1 shared G. MinasoviD· 1 shared H. Steven SeifertiD· 1 shared J. S. BrunzelleiD· 1 shared Julia RosecransiD· 1 shared K.J.F. SatchelliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMicrobiology

Alexei V. SavchenkoORCID

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2 papers

Recent·Most cited

MicrobiologyMicrobiology SpectrumPeer-reviewedJul 7, 2025

Structural and functional analyses of SARS-CoV-2 Nsp3 and its specific interactions with the 5' UTR of the viral genome

Sofia Lemak, T. Skarina, Robert Flick…·Alexei V. Savchenko

This study analyzes the structural and functional interactions of SARS-CoV-2 Nsp3 with the 5' UTR of the viral genome, identifying key domains involved in binding and translocation.

9 citationstop 3%

virusstructural biology

𝕏 PostBluesky

MicrobiologyProtein SciencePeer-reviewedFeb 19, 2025

Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains

Mónica Rosas‐Lemus, G. Minasov, J. S. Brunzelle…·K.J.F. Satchell

The paper resolves the x-ray structure of SARS-CoV and SARS-CoV-2 SUD-N/M domains and shows they have rotational flexibility, with disulfide bonds absent in pangolin-SARS and related viruses.

2 citations

structural biologyexperimental assay

𝕏 PostBluesky