Author

Tuuli Kirkinen

University of HelsinkiORCID 0009-0009-7486-5326Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:Drosophila· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:genetic perturbation / CRISPR· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Ville HietakangasiD· 3 shared Jaakko MattilaiD· 2 shared Kateryna GaertneriD· 2 shared Krista KokkiiD· 2 shared Onur DeniziD· 2 shared Pekka KatajistoiD· 2 shared Simon AnderssoniD· 2 shared Atte Hallasaari· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersPhysiology

Ville HietakangasORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

PhysiologybioRxivPreprintNov 4, 2026

Nutrient-responsive midgut turnover is spatially controlled by serotonin signaling

Nicole Lamichane, Petteri Borgman, Terhi Rintakangas…·Ville Hietakangas

The paper shows serotonin signaling spatially controls nutrient-responsive midgut turnover in Drosophila by regulating enteroblast maturation and morphological changes through the 5HT7 receptor.

DOI 10.64898/2026.11.03.763885

Drosophilaproteomics

𝕏 PostBluesky

PhysiologybioRxivPreprintNov 4, 2026

mTORC1-dependent control of Hedgehog signaling mediates nutrient-responsive licensing of intestinal stem cell differentiation

Gaia Fabris, Simon Biaudet, Atte Hallasaari…·Ville Hietakangas

This study identifies an mTORC1-PWP1-Hedgehog circuit that links nutrient metabolism to intestinal stem cell differentiation in Drosophila, showing its role in aging and tissue renewal.

DOI 10.64898/2026.10.29.762847

Drosophilagenetic perturbation / CRISPR

𝕏 PostBluesky

Cell BiologyThe EMBO JournalPeer-reviewedJul 11, 2026

Spalt-related is an integrated stress response-activated inhibitor of mTORC1-mediated growth

Onur Deniz, Liu Y, Tuuli Kirkinen…·Ville Hietakangas

This study identifies Spalt-related (Salr) as a negative regulator of growth and lipid storage, activated through the integrated stress response and converging with FoxO to promote catabolism during nutrient stress.

DOI 10.1038/s44318-026-00858-1

Drosophilaproteomics

𝕏 PostBluesky