Author

Xin Jiang

Broad InstituteORCID 0009-0009-8053-737XUnclaimed ORCID profile · follow to get notified of new preprints

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Xin Jiang1 paper

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Brian J. WaingeriD· 3 shared Clotilde Lagier‐TourenneiD· 3 shared Aaron HeldiD· 2 shared Chao-Zong LeeiD· 2 shared Corey Aguilar· 2 shared Don W. ClevelandiD· 2 shared Leonard PetrucelliiD· 2 shared Alice S. Chen‐PlotkiniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersNeuroscience

Brian J. WaingerORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 24, 2026

Statins and genetic inhibition of the mevalonate pathway activate an ATF3-STMN2 regenerative program

Matthew Nolan, Sandeep Aryal, I. Sandra Ndayambaje…·Clotilde Lagier‐Tourenne

The paper shows statins and mevalonate pathway inhibition increase STMN2 and ATF3, promoting neuronal regeneration in neurodegenerative disease.

1 citation

humanbulk RNA-seq

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NeuroscienceNeuronPeer-reviewedMar 13, 2023

Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration

Dylan V. Neel, Himanish Basu, Georgia Gunner…·Isaac M. Chiu

This study identifies GSDME as a mediator of mitochondrial damage and axon loss in neurodegenerative diseases, showing its role in ALS and FTD models.

139 citationstop 1%

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NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedDec 1, 2022

Comprehensive preclinical evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9ORF72 disease

Mélanie Jambeau, Kevin D. Meyer, Marián Hruška-Plocháň…·Clotilde Lagier‐Tourenne

This study evaluates human-derived anti-poly-GA antibodies in cellular and animal models of C9ORF72 disease, showing mixed effects on poly-GA levels and disease progression.

12 citations

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