Mosquito-borne diseases and control

This study identifies LRP8 as a receptor for Yellow Fever Virus, showing it facilitates infection and presents a potential therapeutic target.

The paper introduces 3D-Feedy, an open-source membrane feeder for mosquitoes that is cost-effective, portable, and achieves comparable or better performance than commercial alternatives.

This study compares how two Dengue virus serotype 4 strains affect Aedes aegypti life-history traits, finding differential impacts on infection prevalence, fertility, and flight capacity.

This study develops a zwitterionic star-polymer that reduces viral load and joint swelling in murine models of Chikungunya virus infection.

This study identifies FcγRI as the critical Fc receptor mediating antibody-enhanced ZIKV infection of placental macrophages through genetic and functional analyses.

The paper reports new distribution records of mosquito species in Puerto Rico and their implications for vector management.

This study identifies temperature seasonality and altitude as key predictors of avian exposure to WNV and SLEV, revealing conserved susceptibility across avian families.

The paper reports the first whole-genome sequencing of dengue virus from field-caught mosquitoes in southern Brazil, identifying DENV-1 and DENV-2 with evidence of viral adaptation and co-circulation.

This study identifies global patterns of mosquito species introductions and their drivers, revealing 45 non-native species, 27 established, with increased introductions since the mid-20th century.

GeneDrive.jl optimizes vector-borne disease management strategies under climate change by integrating genetic biocontrol and temperature-responsive dynamics.

This paper reports the first urban establishment of Aedes vittatus in Merida, Mexico, highlighting the need for enhanced surveillance of invasive mosquito species.

This study evaluates a Zika virus-like particle (VLP) vaccine in rhesus macaques, showing it reduces early pregnancy loss caused by a highly pathogenic ZIKV strain.

The paper compares TMUV cluster 1 and 2 strains, finding cluster 2 has higher replication efficiency in human cells and induces stronger innate immune responses.

This paper compares multivariate and univariate resilience indicators for early warning of West Nile virus outbreaks, finding multivariate indicators perform better in data-poor scenarios.

This study models the impact of weather on Aedes albopictus oviposition in southern France, finding temperature is key for activity onset and duration, with rain and humidity playing secondary roles in summer.

This study shows that CHIKV macrodomain catalytic activity affects virus replication and transmission in Aedes mosquitoes, with mutation-specific outcomes in different host contexts.

The paper presents a geo-referenced dataset of Aedes mosquito occurrences in Kinshasa, DRC, collected using multiple trapping methods, to support arbovirus vector control strategies.

This study finds that mass-planted large bromeliads in urban areas increase mosquito populations, raising public health risks.

This study identifies time-dependent dengue virus polyprotein processing into multiple capsid forms that disrupt mitochondrial homeostasis, with ursonic acid shown to restore mitochondrial function and inhibit viral replication.

The paper estimates host-to-vector transmission probability for two ZIKV strains from monkey species to mosquitoes, finding squirrel monkeys are more infectious than cynomolgus macaques.

This study shows that Tretinoin inhibits Chikungunya virus infection in vitro, in vivo, and ex vivo by modulating retinoic acid receptor signaling and reducing inflammation.

This study uses a dengue replicon model to show how host pathways are rewired to support persistent RNA replication without stress responses.

The paper identifies variation in virion phosphatidylserine content as the reason for differential GAS6 binding among flaviviruses, explaining ZIKV's unique ability to use AXL for entry.

This study shows that Oropouche virus causes severe congenital malformations and neurodevelopmental issues in embryonic mice, mirroring human fetal cases.

This study detects Japanese encephalitis virus in piggery effluent before clinical outbreaks, showing potential for early warning systems.

This study shows PKM2 reduces JEV replication by interacting with NS1, highlighting a new role for PKM2 in viral neuropathogenesis.

This study identifies mesenteric ischemia and bacterial translocation as key drivers of the severe intoxication phase of yellow fever in humans and animals.

This study evaluates the effects of Simvastatin, Phenytoin, and Ascorbic acid on endothelial dysfunction in Ea.hy926 cells treated with DHF serum, finding that low-dose Simvastatin reduces cell-cell distances and increases cell size.