Insect Resistance and Genetics

This study identifies genetic variants, including copy number variation and cis-regulatory changes, associated with pyflubumide resistance in spider mites through high-resolution genetic mapping and functional experiments.

The paper identifies alternative splicing events in western corn rootworm midguts in response to Bt toxin exposure using RNA-seq and PacBio Iso-Seq.

This paper shows that expressing the scorpion toxin AaHIT in diamondback moth reduces adult lifespan and female egg production, demonstrating a non-cell-autonomous genetic pest management approach.

This paper describes a system for producing insecticidal circular dsRNA in E. coli using viroid scaffolds and introns, demonstrating its effectiveness against Western corn rootworm.

This study identifies core RNAi pathway genes in D. gallinae and demonstrates effective dsRNA-mediated gene knockdown for functional genomics and control target validation.

This study identifies two RDL GABA-receptors in diamondback moths, showing PxRDL1 mediates fipronil sensitivity while PxRDL2 contributes to resistance through differential expression and sensitivity.

This study uses dynamic Bayesian networks to analyze transcriptome time-course data from sub-lethal pyrethroid-exposed Anopheles coluzzii, identifying 44 transcription factors involved in pesticide response.

The paper detects early genetic and transcriptomic changes in sea lamprey exposed to pesticide TFM, showing adaptation without full resistance.

The paper examines genome-wide population genetics of insecticide resistance in navel orangeworms, finding a large selective sweep linked to DDT and pyrethroid resistance genes.

The paper presents the first genome sequence for a thysanopteran insect, providing insights into its biology and evolution as a crop pest.

This study compares the toxicity of Vip3A in vitro and in planta against lepidopteran pests, finding no correlation between the two and highlighting host plant adaptation effects.

The paper identifies a new kdr mutation, F1534L, in Ae. aegypti from Bengaluru, India, co-occurring with other kdr mutations and associated with permethrin resistance.

The paper develops a multiplex PCR method to detect three kdr mutations in Aedes aegypti and validates it against allele-specific PCR with high concordance.

The paper identifies candidate detoxification genes in Drosophila by integrating evolutionary and transcriptomic data, finding that EcKLs may function in detoxification and that many P450s are potential detoxification candidates.

The paper shows that pyrethroid resistance alleles in Aedes aegypti decline in frequency when pyrethroid pressure is removed, but the decline varies by strain.

The paper develops a target capture sequencing method and analysis pipeline to genotype the full voltage-gated sodium channel gene in mosquitoes, enabling the discovery of novel insecticide resistance mutations.

This study combines genetic crosses with targeted DNA sequencing to identify resistance alleles in multi-resistant Aedes aegypti mosquitoes exposed to insecticides.

This study identifies genes associated with bendiocarb resistance in Ugandan Culex quinquefasciatus mosquitoes through transcriptomic analysis.

The paper develops and validates an ETAS-PCR assay for detecting tri-allelic Vgsc-L1014F mutations in Culex quinquefasciatus, showing high correlation with established methods.

The paper identifies cis and trans-acting genetic variants affecting survivorship in Drosophila melanogaster exposed to ryanoid insecticides.

This study shows that silencing cathepsin L in aphids reduces their protein content and affects ladybug growth, highlighting the importance of prey nutritive value in RNAi-based pest control.

The paper uses experimental evolution in spider mites to map genetic loci underlying pesticide resistance and host plant adaptation, revealing polygenic and locus-specific mechanisms.

The paper links insecticide resistance in Drosophila melanogaster to structural variants and selective sweep loci using genome-wide association studies.

The paper examines transcriptomic responses of Colorado potato beetles to imidacloprid and chlorothalonil, finding similar up-regulation of detoxification genes.

The paper quantifies permethrin resistance and kdr alleles in Florida Aedes aegypti and Ae. albopictus strains, finding widespread resistance and strong correlation between kdr alleles and resistance ratios.

The paper presents the genome of the Colorado potato beetle to study its rapid evolutionary changes, herbivory adaptations, and insecticide resistance mechanisms.

The paper investigates the roles of insect and microbial enzymes in imidacloprid metabolism in Drosophila melanogaster using genetic and mass spectrometry methods, finding microbial contributions to nitro-reduced metabolites and excretion of toxic products.

The paper investigates genetic factors underlying imidacloprid resistance in Drosophila melanogaster using genomic and transcriptomic data, identifying Cyp6g1 and Cyp6g2 as key contributors.