3D Printing in Biomedical Research

Tissue-Derived Insoluble Type I and Type II Collagen Inks for 3D Printing of Fibrillar Collagen Scaffolds

This paper develops tissue-derived insoluble type I and type II collagen inks for 3D printing of scaffolds, showing viable cell responses and dimensional stability.

In-Chip Volumetric Printing of Collagen-I Scaffolds for Perfusable and Stretchable Mammary Tissue Models

This paper develops a method to print collagen-I scaffolds directly inside organ-on-chip devices, enabling perfusable and stretchable mammary tissue models with compartmentalized fluidic control.

Spatial engineering of posterior signaling centers in cerebral organoids via controlled morphogen exposure within hydrogels

This paper introduces a hydrogel platform to spatially engineer posterior signaling centers in cerebral organoids through controlled morphogen exposure, improving spatial organization and cellular diversity.

Growing Macroscopic Functional Human Tissues on 3D Printed Peptide Hydrogels

This study demonstrates growing macroscopic functional human tissues on 3D-printed peptide hydrogels, enabling centimeter-scale neural organoids and directional axonal communication.

Fallopian Tube Organoid-Integrated Microfluidic Platform for Real-Time Imaging and Outflow Analysis

This paper develops a microfluidic platform integrating fallopian tube organoids to study epithelial function and disease, showing viable cultures and comparable cell health to intact organoids.

An Innervated and Vascularized HNSCC-on-a-Chip Model Built on Defined and Tunable Engineered Extracellular Matrices

This paper develops an HNSCC-on-a-chip model with tunable engineered extracellular matrices, vasculature, and innervation to study tumor behavior and therapeutic responses.

Excluded Volume Effect-induced Shrinkage for Resolution Enhancement of Hydrogel Bioconstructs

This paper introduces EVER, a post-processing strategy that enhances hydrogel bioconstruct resolution through shrinkage induced by excluded volume effects, achieving significant dimensional reduction while maintaining cell viability.

Rapid thermoforming of polycarbonate cell culture accessories from 3D printed molds

This paper introduces a method to rapidly create customized, autoclavable cell culture accessories using polycarbonate thermoforming from 3D printed molds, demonstrating compatibility with human iPSC culture and differentiation.

Spheroid surgery: a first-generation micromanipulation platform for extracting viable cell clusters from the outer layers of hydrogel-embedded spheroids

This paper introduces a micromanipulation platform to extract viable cell clusters from hydrogel-embedded 3D spheroids without disrupting the parent structure.

Mechanoscribed Xolography for Multiscale Mechanical Patterning of Cell-laden Hydrogels

This paper introduces a 3D bioprinting technique called Mechanoscribed Xolography to create cell-laden hydrogels with controlled mechanical heterogeneity and monitors their evolution over time.

Fast computational screening of extrusion parameters for bioprinting of skeletal myoblasts in alginate hydrogel

The paper develops a finite element-Gaussian process framework to rapidly predict optimal extrusion parameters for bioprinting skeletal myoblasts in alginate hydrogel, identifying conditions that minimize cell damage while maintaining flow rate.

Plant cell-based 4D engineered living materials

This paper demonstrates the use of plant cells to create adaptive, programmable living materials with photosynthetic and electrochemical functionalities.

3D-bioprinted skeletal muscle with tailored myofibre architecture

This paper develops a 3D bioprinting method to create engineered skeletal muscle with controlled myofibre architecture, demonstrating functional tissue with various fibre orientations.

Development of a Low-cost Extrusion Multi-nozzle 3D Bioprinter for Complex Constructs

This paper develops a low-cost, multi-nozzle 3D bioprinter capable of printing up to 10 different bioinks with high positional accuracy and repeatability.

Integration of In-Line Light-Mediated Cell Activation in Extrusion-Based Bioprinting: A New Biofabrication Strategy for Bone Tissue Engineering

This paper integrates broadband light stimulation into bioprinting to enhance osteogenic differentiation and vascularisation in 3D cell cultures.

Oxygen-permeable microwell plates for high-throughput spheroid culture

This paper develops oxygen-permeable microwell plates using PMP to improve spheroid culture by enhancing oxygenation and reducing hypoxia.

LigHTS: Massively Parallel Biomimetic Photo-Functionalization for Imaging-Based Ultra-High-Throughput Screening

This paper introduces LigHTS, a method to create biomimetic hydrogels in standard microplates for high-throughput screening, enabling tunable thickness and topography with improved reproducibility.