Neuroscience and Neural Engineering

This study evaluates how biomimetic microstimulation affects neural activity in sensory cortices, finding that amplitude modulation reduces stimulation-induced depression and improves onset/offset detection.

This study examines how cortical neurons in awake primates respond to intracortical microstimulation, revealing complex dynamics including excitatory responses and inhibitory periods.

This paper introduces a mesh microelectrode array for non-invasive electrophysiology in neural organoids, demonstrating long-term culture and electrical activity recordings.

This paper introduces a cranial implant that stabilizes brain movement in behaving rodents, improving the success rate of whole-cell patch-clamp recordings.

The paper introduces a wireless sensor for in vivo brain activity recording using an ion-sensitive field effect transistor and validates its performance in rodents.

This study develops a stable neural recording method for mice, enabling long-term tracking of single-neuron activity and analysis of aging effects using machine learning.

This paper introduces a wearable closed-loop neuromodulation system for recording single-neuron and local field potential activity in freely-moving humans.

This paper develops a method to record and optogenetically manipulate neural activity in awake, behaving marmosets, demonstrating its use in recording from V1 and V6 and showing behavioral effects from optogenetic activation in V6.

This study shows that young rats exhibit reduced inflammatory response and better recording performance with neural implants compared to adult rats.

This paper demonstrates that a graphene-enhanced organic photovoltaic device restores visual function in a rat model of retinitis pigmentosa without significant inflammation.

This paper presents a fully desktop-fabricated flexible graphene ECoG array that can record brain activity in mice with long-term functionality and customizable electrode layouts.

This paper introduces a neural implant that enables simultaneous two-photon imaging and extracellular electrophysiology in freely moving animals, showing a positive correlation between optical and electrical recordings.

This study demonstrates that high-fidelity electrical stimulation of human retinal ganglion cells is achievable with extracellular stimulation, validated through ex vivo experiments and comparison to macaque retina results.

This paper demonstrates a magnetomechanical approach using magnetic nanodiscs to achieve wireless neuronal stimulation in vitro and untethered deep brain stimulation in vivo without implants or genetic modification.

The paper develops a 3D printed skull cap and benchtop fabrication method for custom microwire microelectrode arrays to enable low-cost, repeatable, and accurate multi-region recordings in rats.

The paper develops a system integrating implantable brain stimulation devices with wearable electronics for adaptive stimulation and real-time analysis in natural environments.

The paper introduces E-Cannula, a tool for simultaneous electrical and optical recording in the hippocampus, revealing anatomical diversity in sharp-wave ripples and their association with distinct cell assemblies.

This study uses microstimulation in V1 of behaving monkeys to investigate spatio-temporal neural activity patterns and their relation to visual responses and saccades.

This study benchmarks spike sorting performance in the presence of spike collisions using synthetic data, finding that all methods struggle with detecting synchronous spikes from neurons with similar signals.

This study examines neural and vascular recovery in aged mice after ultraflexible electrode implantation, finding vascular remodeling precedes neural signal recovery and normalizes by six weeks.

This paper introduces a deep contractive autoencoder for online spike sorting, achieving over 90% accuracy and outperforming offline methods.

This paper introduces eSee-Shells, transparent polymer skulls with integrated electrode arrays for long-term multimodal neural recordings in mice.

The paper introduces a GUI toolkit for analyzing LFP data from HD-MEA recordings, demonstrating its utility in detecting seizure propagation in Scn1aHet mice.

This paper demonstrates a noninvasive method to stimulate peripheral nerves using temporally-interfering electrical fields, achieving effective stimulation with lower current amplitudes than traditional methods.

This paper introduces a stretchable mesh electrode system for long-term electrical interfacing with human cortical organoids, demonstrating stable performance and successful integration with neural tissue.

This paper presents a method for high-density single-unit recording in human cortex using Neuropixels probes, achieving 596 single units across 11 recordings in 8 participants.

This paper introduces a minimally invasive coaxial microprobe for multi-modal neural interfacing, enabling efficient electrical and optical interrogation with reduced inflammation.

This study evaluates how tactile percepts from intracortical microstimulation (ICMS) in the human somatosensory cortex adapt over time with different stimulation protocols.

This paper optimizes visual prosthetic stimulation using patient feedback and Bayesian optimization, improving perceived image quality in healthy subjects.

pyNeurode provides a real-time spike sorting framework for neural signals with high accuracy and scalability, supporting up to 128 channels and integrating with Open Ephys.