Topic · Information Systems and Management · Decision Sciences
Scientific Computing and Data Management
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
181 papers
- NeurosciencebioRxivPreprint
Shaping a Collaborative, Sustainable, Accessible, and Reproducible Future for Computational Modeling
Manuel Guidon, Dustin Kaiser, Elisabetta Iavarone…·Esra Neufeld
The paper introduces o2S2PARC, an open-source platform for computational modeling and analysis, highlighting its features, applications, and adoption.
- BioinformaticsbioRxivPreprint
dnaudit + Pydnaweb: A lightweight text-based planning and documentation workflow for genetic cloning with automatic verification
Patrícia Ataíde, Faezeh Ghasemi, Paulo César Silva…·Björn Johansson
dnaudit and Pydnaweb provide a no-code, reproducible workflow for documenting and validating genetic cloning strategies with automated verification.
DOI 10.1101/2025.05.31.657172 - Systems BiologybioRxivPreprint
FAIRification of computational models in biology
Irina Balaur, David Phillip Nickerson, Danielle Welter…·Dagmar Waltemath
The paper proposes adapting FAIR indicators to assess and improve the quality and transparency of computational models in biology.
2 citations - GenomicsbioRxivPreprint
FlowAgent: A Modular Agent-Based System for Automated Workflow Management and Data Interpretation
Joshua Philpott, Alina Kurjan, Adam P. Cribbs
FlowAgent automates bioinformatics workflows with an agent-based system, improving reproducibility and accessibility through intelligent decision-making and natural language interfaces.
- NeurosciencebioRxivPreprint
AIRUS: a simple workflow for AI-assisted exploration of scientific data
The paper introduces AIRUS, an AI-assisted workflow enabling scientists to use LLMs for hypothesis generation, coding, and result interpretation without extensive AI expertise.
DOI 10.1101/2025.02.23.639768 - BioinformaticsbioRxivPreprint
pipemake: A pipeline creation tool using Snakemake for reproducible analysis of biological datasets
Andrew E. Webb, Scott Wolf, Ian M. Traniello, Sarah D. Kocher
pipemake creates modular Snakemake workflows for reproducible biological data analysis, reducing hands-on time and enabling flexible pipeline adaptation.
DOI 10.1101/2024.12.20.629758 - BioinformaticsbioRxivPreprint
Bio-medical Big Data Operating System (Bio-OS): An Integrated Data Mining Environment for Data Intensive Scientific Research
Ji‐Long Liu, Liguang Yang, Qingyu Xiao…·Yixue Li
BioOS provides a cloud-native platform for reproducible biomedical research by integrating data, code, tools, and environments into workspaces, enhancing data integrity and accessibility.
4 citations - BioinformaticsbioRxivPreprint
BMAP: a comprehensive and reproducible biomedical data analysis platform
Yongyong Ren, Zhiwei Cheng, Leijie Li…·Hui Dong Lu
BMAP provides a platform for managing and analyzing biomedical data, improving reproducibility and efficiency in research workflows.
7 citations - BioinformaticsbioRxivPreprint
Maloja: simple and scalable Snakemake workflow orchestration in the cloud
Joseph Giustizia, Wilson Hodgson, Cameron Andress…·Tony Kess
Maloja simplifies cloud deployment of Snakemake workflows by automatically scaling AWS resources, tested on ecological genomics tasks.
DOI 10.1101/2024.06.28.601236 - BioinformaticsbioRxivPreprint
Playbook Workflow Builder: Interactive Construction of Bioinformatics Workflows from a Network of Microservices
Daniel J. B. Clarke, John Erol Evangelista, Zhuorui Xie…·Avi Ma’ayan
The paper introduces a web-based platform for building bioinformatics workflows using APIs, enabling hypothesis generation across multiple data sources.
- BioinformaticsbioRxivPreprint
Improving the Reliability and Quality of Nextflow Pipelines with nf-test
Lukas Forer, Sebastian Schönherr
The paper introduces nf-test, a testing framework for Nextflow pipelines that improves reliability, reduces test time, and enhances software quality through modular and efficient testing.
- BioinformaticsbioRxivPreprint
BioInformatics Agent (BIA): Unleashing the Power of Large Language Models to Reshape Bioinformatics Workflow
Xin Qi, Quyu Kong, Hongyi Ji…·Yinqi Bai
This paper introduces BIA, an intelligent agent using LLMs to automate bioinformatics tasks, demonstrating its effectiveness with scRNA-seq data and outlining strategies for improvement.
18 citations - BioinformaticsbioRxivPreprint
Replicating a High-Impact Scientific Publication Using Systems of Large Language Models
Dennis Bersenev, Ayako Yachie‐Kinoshita, Sucheendra K. Palaniappan
This study attempts to reproduce a high-impact publication using a multi-agent system of LLMs, highlighting both capabilities and challenges in automating scientific research.
- NeurosciencebioRxivPreprint
Spyglass: a framework for reproducible and shareable neuroscience research
Kyu Hyun Lee, Eric L. Denovellis, Ryan Ly…·Loren M. Frank
Spyglass provides a reproducible and shareable framework for neuroscience research, enabling data reuse and analysis across labs using standardized formats and pipelines.
13 citations - BioinformaticsbioRxivPreprint
BioMANIA: Simplifying bioinformatics data analysis through conversation
Zhengyuan Dong, Han Zhou, Yifan Jiang…·Yang Young Lu
BioMANIA provides a codeless, AI-driven bioinformatics pipeline that simplifies omics data analysis by interpreting natural language instructions and integrating existing tools.
- BioinformaticsbioRxivPreprint
Flow: a web platform and open database to analyse, store, curate and share bioinformatics data at scale
Charlotte Capitanchik, Sam M Ireland, J. Alex Harston…·Jernej Ule
Flow provides a web platform and database for managing and analyzing large-scale bioinformatics data, addressing challenges in data processing, quality, and accessibility.
3 citations - BioinformaticsbioRxivPreprint
A Multi-omics Data Analysis Workflow Packaged as a FAIR Digital Object
Anna Niehues, Casper de Visser, Fiona A. Hagenbeek…·Alain J. van Gool
The paper develops a multi-omics data analysis workflow packaged as a FAIR Digital Object to improve reproducibility and reuse in computational research.
1 citation - BioinformaticsbioRxivPreprint
BioModelsML: Building a FAIR and reproducible collection of machine learning models in life sciences and medicine for easy reuse
Divyang Deep Tiwari, Nils Hoffmann, Kieran Didi…·Rahuman S. Malik‐Sheriff
This paper introduces a protocol to create a FAIR collection of machine learning models in life sciences and medicine, aiming to improve reproducibility and reuse through community curation.
- BioinformaticsbioRxivPreprint✦ In-depth digest
The ENCODE Uniform Analysis Pipelines
Benjamin C. Hitz, Jin-Wook Lee, Otto Jolanki…·J. Michael Cherry
ENCODE's containerised Workflow Description Language pipelines for ChIP-seq, ATAC-seq, DNase-seq, RNA-seq variants, Hi-C and bisulfite sequencing run on cloud or local clusters, with documented compute costs and provenance.
- BioinformaticsbioRxivPreprint
Minuteman - A versatile cloud computational platform for collaborative research
Xin Kai Li, Joydeep Charkaborty, Michael Jameson…·Dhawal S. Jain
Minuteman provides a secure cloud platform for collaborative biomedical data analysis with features for data management, access control, and interactive exploration.
DOI 10.1101/2023.01.21.514916 - BioinformaticsbioRxivPreprint
The Labbing Project: A database management application for neuroimaging research
The Labbing Project presents a web application for neuroimaging data aggregation and preprocessing, designed to simplify data management for researchers with limited programming experience.
DOI 10.1101/2023.01.02.522426 - BioinformaticsbioRxivPreprint
Dissecting Complexity: The Hidden Impact of Application Parameters on Bioinformatics Research
Mikaela Cashman, Myra B. Cohen, Alexis L. Marsh, Robert W. Cottingham
This paper examines the impact of application parameters on bioinformatics tools and proposes a methodology to systematically explore these parameters across different tools and scientific inquiries.
1 citation - BioinformaticsbioRxivPreprint
Meta-analysis of (single-cell method) benchmarks reveals the need for extensibility and interoperability
Anthony Sonrel, Almut Luetge, Charlotte Soneson…·Mark D. Robinson
This paper meta-analyzes single-cell method benchmarks to identify challenges in extensibility, interoperability, and reproducibility.
- BioinformaticsbioRxivPreprint
saks-nf: A json solution for Nextflow pipeline construction
Xinming Zhuo, Nicholas Renzette, Gregory Omerza
saks-nf simplifies Nextflow pipeline creation using JSON, enabling non-programmers to build and manage complex workflows without coding.
DOI 10.1101/2022.09.19.508305