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This study develops N-Amino Peptide-Graphene Quantum Dot loaded small extracellular vesicles to target tauopathies, showing improved specificity and efficacy in inhibiting tau aggregation and transmission.

This paper introduces a novel mutagenesis method using BaRecJ's endonuclease and exonuclease activities, showing broader mutation spectra and improved trait-associated gene identification in E. coli and S. cerevisiae.

The paper introduces PULSE, a device for targeted ultrasound-mediated delivery of drugs and genes in tumors, showing improved transfection and perfusion in vitro and phantom tests.

This paper introduces MaMBA, a modular DNA barcoding strategy for antibodies, enabling multiplexed in situ protein imaging and high-throughput biomolecule detection.

This study develops circular guide RNAs (cgRNAs) and Cas13d-encoding mRNA for efficient RNA editing of Adar1 in triple-negative breast cancer, showing improved stability and therapeutic efficacy.

This study shows integrating non-sewered sanitation systems with sewered wastewater treatment plants reduces operating energy costs and improves treatment efficiency.

This paper develops a microphysiologic model of the cervical epithelium that replicates microbial, immunologic, and pathogenic features of STIs caused by Chlamydia and Neisseria.

This paper introduces a supramolecular self-assembly method for site-specific antibody conjugation using coiled-coil peptides, demonstrating improved uniformity and efficacy in targeting HER2+ tumors.

This study develops site-specific antibody-gas vesicle conjugates as durable cancer-targeting ultrasound contrast agents, validated through testing on cancer cell lines and tumor-bearing mouse cells.

The paper introduces the Dayhoff Atlas, a resource with large protein sequence datasets and generative models to improve protein design and prediction.

This paper introduces DNA-based hydrogel microparticles with tunable mechanical properties for 3D cellular systems, showing they can be remodeled by fibroblast spheroids based on their stiffness.

This paper develops hybrid peptide-DNA nanomaterials that neutralize influenza viruses more effectively than free peptides by enhancing multivalent binding and reducing toxicity.

This paper uses hyperspectral imaging to analyze banana peels as a surrogate model for detecting skin changes, demonstrating its potential for dermatology applications.

This paper introduces HAM-SVD, a method for ultrafast ultrasound imaging of gas vesicles that improves signal-to-background ratio compared to existing techniques.

This study develops a two-phase FSI model of mucociliary clearance with non-Newtonian mucus and realistic cilia motion, showing improved mucus transport.

The paper proposes a PAM-CNN model to classify muscle fatigue using sEMG signals, achieving 95.6% accuracy in testing.

This study evaluates the safety and feasibility of combining ultrasound histotripsy with liver organoid implantation in rodents to treat congenital metabolic liver disease.

This paper introduces snuABE, a single-nucleotide resolution ABE that reduces bystander effects through engineered ADAR and tagRNA design, achieving precise A-to-G editing in human cells.

This study evaluates the biocompatibility of large-area 2D electronic materials with mouse neural stem cells, finding they support viability and neuronal differentiation, with MoS2 promoting significant neuronal maturation.

This paper develops synthetic G-quadruplex elements to precisely control mammalian recombinant protein expression across different hosts and molecular formats.