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The paper explains the sister repulsion phenomenon in Patterson's f-statistics by proposing a demographic model involving gene flow from an external source.

This paper develops and validates variant classification guidelines for animals, improving the accuracy of pathogenicity assessment in cats and eight other species.

The paper identifies EZH2 and SOX2 as key genes in LUAD through differential expression analysis and pathway enrichment, suggesting EZH2 as a potential therapeutic target.

This study shows that inhibiting DNA repair pathways with AZD7648 improves gene insertion efficiency in airway stem cells for CFTR correction, but may introduce toxicity.

The paper responds to criticisms of their reference-free analysis method by addressing claims about high-order epistasis and methodological equivalences.

The paper identifies a locus in one Xiphophorus species that represses an oncogene from another species, providing insights into hybrid incompatibility and pigment cell regulation.

The paper investigates the role of the Raf/LIN-45 C-terminal distal tail segment in regulating signaling in C. elegans, identifying its inhibitory functions through genetic and structural analyses.

The paper investigates the deployment of tethered gene drives in continuous space, finding that drive wave interference must be avoided to ensure successful suppression.

This paper demonstrates the use of CRISPRi/a in zebrafish to modulate gene expression and study gene function in pigmentary and growth phenotypes.

The paper shows that constitutive SKN-1 activation in C. elegans leads to serotonin deficiency, causing apathy toward pathogens and reduced survival.

This study examines how genetic variation in vgll3 affects maturation age in Atlantic salmon, showing sex- and context-dependent expression patterns and interactions with other genes.

The paper uses genome analysis to trace the paternal origin of the Aba royal family in Hungary to East Eurasia, linking them to Mongolian ancestry and medieval Hungarian elites.

The paper shows SAX-7/L1CAM antagonizes ERK signaling in both neuronal and non-neuronal processes in C. elegans.

This study shows that NuRD chromatin remodeling is essential for repairing exogenous DNA damage in C. elegans germline, with defects leading to reduced fertility and aneuploidy.

This study identifies SNPs in PAEP, KRT10, and BMP7 genes associated with reproductive traits in Kele pigs and identifies favorable genotypes and diplotypes.

This study integrates Ayurveda with modern medical data to classify rare diseases into six clusters, revealing potential ciliopathies in specific clusters.

This study identifies Ripply3 overdosage as a cause of mid-face shortening in Down syndrome models through Tbx1 downregulation during branchial arch development.

The paper identifies a new ALPK1 variant causing ROSAH syndrome and shows it has altered activation by different metabolites, explaining autoinflammatory episodes.

This paper shows that family-based GWAS estimates are not generally unbiased for average causal effects but can provide insights into Mendelian segregation's contribution to population-level trait variance.

This study shows SMARCAD1 resolves R-loops at replication forks, preventing genome instability and cancer mutations.