Yan Wu

Inhibition of integrin αvβ8-mediated TGFβ activation and active-TGFβ blockade promote anti-tumor immunity through distinct biological mechanisms

The paper shows that blocking integrin αvβ8 suppresses TGFβ in tumor-draining lymph nodes and enhances DC-T cell activation, offering a new immunotherapy strategy distinct from TGFβ ligand blockade.

Mitotically Driven Cytoskeletal Reorganization Governs Zebrafish Left-Right Organizer Detachment from EVL and Lumen Morphogenesis

The paper shows that early cytokinesis drives cytoskeletal reorganization in zebrafish Kupffer's vesicle, enabling lumen formation and detachment from the enveloping layer.

Association analysis of PAEP, KRT10 and BMP7 Genes SNPs with reproductive traits in Kele pigs

This study identifies SNPs in PAEP, KRT10, and BMP7 genes associated with reproductive traits in Kele pigs and identifies favorable genotypes and diplotypes.

Specific Mitotic Events Drive Cytoskeletal Remodeling Required for Left-Right Organizer Development

This study shows that specific mitotic events drive cytoskeletal remodeling necessary for Left-Right Organizer development in zebrafish.

A novel platform of RNA 2'-O-methylation high-throughput and site-specific quantification tools revealed its broad distribution on mRNA

The paper introduces NJU-seq and Nm-VAQ to quantify RNA 2'-O-methylation sites in mRNA, identifying thousands of new sites and validating their presence in human and mouse cell lines.

Investigation of novel functions of three genes in oriental river prawn, Macrobrachium nipponense: Molecular Cloning, Expression, and In situ Hybridization Analysis

This study investigates the functions of three genes in male sexual development and androgenic gland formation in M. nipponense using molecular cloning, expression analysis, and in situ hybridization.