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This study shows that placental hIGF1 nanoparticle treatment in guinea pigs reduces FGR-related kidney structural and signaling pathway changes.

This study evaluates the efficacy of a synthetic kisspeptin analog, C6, in reversing reproductive dysfunction in a mouse model of hyperprolactinaemia, showing it is as effective as native kisspeptin.

This study uses image registration to transform DTI-derived muscle architecture from an extended to a flexed position, showing no significant change in average architectural parameters.

This study identifies caspase-1 as a driver of vascular inflammation and hypoperfusion in intravascular hemolysis, showing its role in endothelial-leukocyte recruitment and microvascular dysfunction.

The paper introduces synthetic haemolymphs (nutribloods) to study how nutrient profiles affect microbial growth in insect-pathogen interactions.

This study evaluates the effect of soleus push up exercise on glucose tolerance in prediabetic individuals, finding a 32% reduction in postprandial glucose excursion during oral glucose tolerance tests.

This study investigates how different rapamycin dosing schedules affect physical performance and metabolic outcomes in mice undergoing voluntary exercise training.

This study found that spinal cord transcutaneous stimulation during an exercise-based priming protocol improved lower limb maximal performance compared to sham stimulation, but did not affect torque steadiness.

This study shows dopamine D2 receptors in zebrafish gill chemoreceptors reduce hypoxic responses through adenylyl cyclase, linking dopamine modulation to oxygen sensing evolution.

This study shows that muscle-specific PolG dysfunction causes mitochondrial dysfunction and cachexia by activating the mtISR and altering the mitochondrial folate cycle.

This study shows that inducing a torpor-like state in mice slows blood epigenetic aging and improves healthspan by reducing core body temperature.

This study shows that inhibiting NHE-1 with rimeporide reduces right ventricular hypertrophy, pulmonary vascular remodelling, inflammation, and fibrosis in a rat model of pulmonary arterial hypertension.

This study identifies that acute kidney injury causes hypoxemia through intravascular neutrophil retention in lung capillaries, reducing blood flow without lung edema.

The paper investigates the role of the medial olivocochlear reflex in human auditory perception by measuring ear, brain, and behavioral responses to intensity changes.

This study characterizes native human pancreatic mesenchymal stromal cells (npMSCs) in type 1 diabetes, finding increased npMSC density around insulin-containing islets and reduced density around insulin-deficient islets in diabetic individuals.

This paper examines RBC morphology and proteomics in mice, finding no significant differences in shape or protein content that could explain changes in O2 permeability observed in prior studies.

This paper develops a reaction-diffusion model to simulate O2 offloading from murine red blood cells, showing that membrane O2 permeability must decrease to explain observed kHbO2 reductions in knockouts.

This study identifies glycoRNA as a novel component of the alveolar epithelial glycocalyx and shows its role in barrier regulation and viral infection.

This paper investigates O2 permeability in murine red blood cells, showing that membrane channels, not lipid diffusion, are critical for O2 transport, with AQP1 and RhAG contributing significantly.

This study examines salivary GDF15 levels and their associations with biopsychosocial factors and stress reactivity in healthy adults.