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This study investigates how β1/β4 subunits and the RKK segment of Slo1 regulate BK channel gate opening through electrostatic interactions.

This study shows that losartan improves survival in male Fbn1mgR/mgR mice when started at 50 days old but not at 24 days, while no benefit was seen in females.

This study examines how degraded water optical properties affect light availability and photosynthetic energy in corals, leading to mortality and habitat contraction in Orbicella faveolata.

The paper examines changes in human liver size and function during pregnancy and weaning, finding growth during pregnancy and regression post-weaning, with bile acids potentially involved.

This study shows that time-restricted feeding near dawn alters long-term mouse behavior through SCN GABAergic neurons by affecting exosome-related genes and Kcc2.

This study shows EIF2A protects pancreatic beta cells from ER stress by rescuing translation inhibition and reducing apoptosis.

This study links high daily temperatures to increased stress hormone levels in Southern pied babblers, indicating acute heat stress responses above 38°C.

The paper uses total-body PET scans to analyze dynamic skeletal energy metabolism networks in mice, revealing unique glucose metabolism patterns across bones and their complex interactions.

This study examines the cardiac phenotype of MK2-deficient mice, finding altered autonomic regulation, increased metabolic gene expression, reduced mitochondrial Ca2+-sensitivity, and delayed hypertrophic remodeling in response to pressure overload.

This study shows leptin regulates glucose homeostasis through the canonical Wnt pathway in zebrafish and mice.

The paper identifies a local innate B cell population that drives antibody production and chronic rejection in lung transplants using single-cell transcriptomics.

This study shows that Phox2b27Ala/+ mice exhibit obstructive and mixed apneas, likely due to hypoglossal dysgenesis, in addition to central apneas and hypoventilation.

This study shows that stimulating soluble guanylate cyclase (sGC) with BAY41-8543 reduces skeletal and cardiac muscle dysfunction in mdx mice, suggesting sGC as a therapeutic target for Duchenne muscular dystrophy.

The paper uses microCT imaging to characterize arterial patterns and evaluate how meal-related shape changes affect gastric regions in rats.

This study examines how oral amino acid intake affects Achilles peritendinous amino acid concentrations in young and older adults, finding modest increases and age-related differences in some amino acids but no significant impact on pro-collagen I1.

This study investigates the role of CNGL channels and cGMP signaling in hypoxia response in adult Drosophila, finding impaired recovery and altered CNS K+ dynamics in CNGL mutants.

This study examines AGO2's role in RNAi by depleting it in Blattella germanica and analyzing siRNA distribution and effects on development.

This study examines how intravenous magnesium sulfate affects calcium-regulating hormones and electrolytes in healthy horses, finding increased urinary excretion and altered hormone levels.

This study shows that high-intensity interval training changes the proteome and acetylome of human skeletal muscle, affecting metabolism and contraction processes.

This study uses intravital microscopy to examine how blood flow affects decellularized nephron scaffolds after transplantation, revealing increased microvascular permeability and scaffold damage.