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This study examines how head orientation affects vestibular signal modulation of paraspinal muscle activity during walking, finding reduced coherence and gain in leftward head orientation.

This paper identifies GPR35 as a target for non-opioid analgesics by showing it inhibits TRPA1-mediated colonic hypersensitivity through suppression of Substance P release.

This study shows that liver-specific LXR inhibition reduces HDL levels and reverse cholesterol transport in cholesterol-fed mice by decreasing LXR-target gene expression.

This study identifies FoxO1-dependent autophagy as a conserved mechanism for regression of physiological cardiac hypertrophy across species.

This study examines the development and variation of trunk wrinkles in Asian and African elephants, linking them to behavioral, environmental, and biomechanical factors.

This study tests if cardiac phase affects threat perception in immersive VR but finds no significant distance or fear differences between systole and diastole.

This study shows that pneumonia increases glucagon levels, which damages endothelial cells and promotes blood clotting, leading to cardiovascular issues.

The paper maps uterine calcium dynamics in live mice across the estrous cycle using a calcium reporter and imaging, revealing phase-dependent initiation patterns of uterine excitations.

This study estimates Achilles tendon twist in vivo by stimulating individual triceps surae muscles and analyzing ultrasound displacement patterns.

This paper identifies a three-dimensional extracellular matrix cage formed by laminin and collagen IV that anchors megakaryocytes in the bone marrow and regulates their maturation and intravasation.

The paper identifies a sexually dimorphic hepatic cycle of VLDL generation and re-uptake in mice and humans, linking VLDLR expression to cardiovascular risk.

This study identifies macrophages as key regulators in bone repair and therapeutic targets for musculoskeletal trauma through multimodal immune cell analysis.

This study shows that calcium transients dampen action potential alternans, and their absence leads to more unstable alternans.

This paper estimates oxygen consumption during outdoor human gait using neural networks, finding that XceptionNet outperforms LSTM for inter-subject estimation.

This study investigates the role of platelet granules in insulin secretion, finding that dense granules, but not alpha granules, are critical for regulating pancreatic beta cell function and glucose metabolism.

This study shows that CD163 deficiency in obese male mice worsens insulin sensitivity by promoting inflammation and iron dysregulation in adipose tissue macrophages.

This paper infers the connectivity of alveolar capillary networks from blood flow dynamics using computational models and simulations.

The paper reanalyzes lifespan studies and finds that short-lived controls overestimate intervention efficacy, proposing a 900-day rule to assess confidence in longevity interventions.

This study compares balance control strategies between older and younger adults using foot force data and simulations, finding older adults rely more on neural feedback due to reduced muscle stiffness.