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The paper presents a general theory of metabolism linking animal taxonomy and size to metabolic scaling laws, showing how the Metabolic Module explains metabolic rate across species.

This study examines age-dependent differences in cardiac hypertrophy and regression in female mice following exercise and detraining, identifying distinct molecular pathways in young versus adult hearts.

This study shows that manipulating the extracellular vesicle biogenesis pathway in male Drosophila somatic cells leads to sex-specific phenotypic changes in offspring.

This study identifies TMC proteins as regulators of crop size and contraction in Drosophila through distinct neuronal pathways involving diuretic hormone and serotonin receptors.

This study compares the effects of high-fat diet and glucocorticoid-induced obesity on metabolic outcomes, finding that the latter prevents fatty liver despite similar adiposity.

This study shows that microbiome-derived queuosine (Q) affects tyrosine metabolism and predator avoidance in mosquito larvae, leading to impaired behavior and survival.

This study identifies DILP8 as a sensor for mature follicle accumulation in Drosophila ovaries, preventing excessive follicles and maintaining oocyte quality through the Lgr3 receptor.

This paper introduces a non-invasive method to detect hyperglycemia in mice using the Urination Index, correlating bedding moisture with blood glucose levels to monitor diabetes progression continuously.

This study shows that liver-derived Yap1 activation during organ repair induces systemic catabolism and muscle loss, similar to cancer cachexia.

This study shows that intestinal fructose metabolism increases GLP-1 secretion, which enhances insulin release and prevents hyperglycaemia, with this effect being impaired in obese diabetic mice.

This study investigates how CIDEB loss-of-function mutations protect against fatty liver disease by enhancing β-oxidation through ATGL and PPARα activation.

The paper develops and optimizes nutrient media for cultivating Artemisia salsoloides and identifies key genes involved in artemisinin-like compound synthesis.

This study shows overnutrition causes hypothyroidism in mice by impairing thyroid hormone biosynthesis and utilization, despite thyroid adaptations, and finds a link between BMI and thyroid vascularization in humans.

This paper develops a protocol for in vitro propagation of the rare plant Thymus calcareus, identifying optimal sterilization, nutrient media, and growth regulator conditions for multiplication and rhizogenesis.

This study monitors beta cell function in vivo over time, showing hyperglycemia disrupts Ca2+ dynamics and hub cells, while GLP1R agonism restores them.

This study shows that homeostatic activation of 26S proteasomes by PKA protects against brain and cardiac dysfunction in Alzheimer's disease mice.

This study shows that α-MSH reduces blood glucose in humans and non-human primates via the MC5R pathway, suggesting it as a potential target for diabetes treatment.

This study identifies and characterizes vitellogenin receptors in Mugil cephalus using orthology, domain analysis, and structural modeling, revealing their evolutionary conservation and functional relevance in reproduction.