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The paper models spin chemistry in mitochondrial Complex I's flavin radical pair, showing kinetic gating by iron sulfur clusters affects singlet yield and spin coherence.

The paper compares miRNA-mRNA profiles across human and murine AKI models to identify shared and specific molecular programs associated with different injury etiologies and biological heterogeneity.

The paper optimizes codon usage for Sapovirus VP1 and VP2 genes in Escherichia coli and performs phylogenetic analysis of twelve human strains.

The paper tracks phage-host interactions in the human gut and finds that DGR-encoding phages interact with multiple bacterial species and show increased nucleotide diversity in their receptor-binding proteins.

The paper introduces six novel gene knock-in mouse lines to label and study molecularly defined cortical intratelencephalic neuron subtypes with distinct projection patterns.

The paper uses structure prediction to annotate the fold of uncharacterized proteins in medicinal leech salivary EVs, identifying one as a Ly-6/uPAR three-finger fold and leaving others unresolved.

Constitutive somatic expression of four tardigrade disordered proteins shortened C. elegans lifespan and healthspan and gave little stress protection. Three of the four reduced polyQ aggregation under hyperosmotic stress.

This study analyzes X-chromosomal STR diversity in the Vedda population, finding significant genetic differentiation from other South Asian groups and highlighting their unique genetic heritage.

This study examines how PPAR genotype affects bone quality and PFOA-induced effects in mice, finding PPAR-dependent changes in bone parameters and osteoblast activity.

The study examines how tree species composition and water availability affect soil nutrient availability through different temporal dynamics in a mixed-species forest.

The paper analyzes DNA captured during siphonophore genome sequencing to identify associated organisms, revealing bacterial and eukaryotic diversity.

This study identifies how two distinct NLR receptors recognize tobamovirus movement proteins, revealing convergent evolution and distinct recognition mechanisms.

This paper presents the first high-quality genome assembly of a cave-dwelling remipede, revealing a repeat-rich genome with extensive gene family turnover and phylogenetic signals.

The paper uses joint QTL mapping to analyze pleiotropy patterns across structured environments in budding yeast, revealing genetic interactions influenced by environmental relationships.

The paper tracks viral infection in Ostreococcus tauri, showing pre-existing genome architecture dictates viral positioning and transcriptional changes during infection.

The paper identifies eight new genes involved in zebrafish glomerular development through transcriptome analysis and CRISPR-Cas9 screening, linking them to proteinuria and glomerular leakage.

This study shows H5N5 viruses have been repeatedly introduced across the Atlantic by high latitude seabirds, with more frequent introductions in fall and spring, and a distinct ecology from H5N1.

This study identifies genomic correlates of APOBEC-associated mutagenesis in ESCC, finding that SBS18 shows the most consistent inverse association, while ZNF750 mutations are linked to higher APOBEC burden.

This paper introduces an AI system for automated small molecule structure elucidation from NMR spectra, combining generative models with reasoning agents to outperform existing tools.

This study uses deep learning to predict cis-regulatory effects of human-specific mutations across 305 tissues, revealing their role in gene expression evolution.