Author

A. A. Adhikari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. S. Devlin· 3 shared S. N. Chaudhari· 3 shared A. S. Banks· 2 shared D. Ramachandran· 2 shared M. D. McCurry· 2 shared C. E. Powell· 1 shared D. K. Li· 1 shared J. A. Marto· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersPhysiology

A. S. Devlin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury

D. K. Li, S. N. Chaudhari, M. Sojoodi, Y. Li, A. A. Adhikari, L. Zukerberg, S. Shroff, S. C. Barrett, K. Tanabe, R. T. Chung, A. S. Devlin

bioRxiv · Mar 24, 2021Physiology

A gut-restricted lithocholic acid analog as an inhibitor of gut bacterial bile salt hydrolases

A. A. Adhikari, D. Ramachandran, S. N. Chaudhari, C. E. Powell, M. D. McCurry, A. S. Banks, A. S. Devlin

The paper develops a gut-restricted BSH inhibitor, AAA-10, which effectively reduces secondary bile acids in mice with minimal systemic exposure.

bioRxiv · Mar 15, 2021Biochemistry

Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases

A. A. Adhikari, T. C. Seegar, S. B. Ficarro, M. D. McCurry, D. Ramachandran, L. Yao, S. N. Chaudhari, S. Ndousse-Fetter, A. S. Banks, J. A. Marto, S. C. Blacklow, A. S. Devlin

This study develops a covalent inhibitor of gut bacterial bile salt hydrolases, showing it reduces BSH activity and deconjugated bile acids in mice.

bioRxiv · May 17, 2019Microbiology