Author

H. S. Tian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Barlas· 1 shared A. Cercek· 1 shared A. D. Goldberg· 1 shared A. E. Hendifar· 1 shared A. J. McRee· 1 shared A. Letai· 1 shared C. Andreu-Agullo· 1 shared C. Famulare· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Barlas

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Therapeutic targeting of SLC6A8 creatine transporter inhibits KRAS mutant and wildtype colon cancer and modulates human creatine levels

I. Kurth, N. Yamaguchi, C. Andreu-Agullo, H. S. Tian, S. Sridhar, S. Takeda, F. C. Gonsalves, J. M. Loo, A. Barlas, K. Manova-Todorova, R. Busby, J. C. Bendell, J. Strauss, M. Fakih, A. J. McRee, , S. F. Tavazoie

RGX-202 inhibits CRC growth by targeting SLC6A8 creatine transporter, reduces creatine and ATP levels, and shows efficacy in multiple tumor models and human trials.

bioRxiv · Apr 26, 2021Cancer Biology

Leukemia cell of origin influences apoptotic priming and sensitivity to LSD1 inhibition

S. F. Cai, S. H. Chu, A. D. Goldberg, S. Parvin, R. P. Koche, J. L. Glass, E. M. Stein, M. S. Tallman, F. Sen, C. Famulare, M. Cusan, C.-H. Huang, C.-W. Chen, L. Zou, K. B. Cordner, , S. A. Armstrong

This study shows that leukemia cell of origin affects apoptotic priming and sensitivity to LSD1 inhibitors, with Evi1 modulating p53 stability and activity.

bioRxiv · May 11, 2020Cancer Biology

Edaravone-Loaded Mesoscale Nanoparticles Treat Cisplatin-Induced Acute Kidney Injury

R. M. Williams, J. Shah, E. Mercer, H. S. Tian, J. M. Cheung, M. Dorso, E. A. Jaimes, D. A. Heller

This study develops edaravone-loaded mesoscale nanoparticles for treating cisplatin-induced acute kidney injury, showing improved renal function and reduced oxidative stress in mice.

bioRxiv · Jan 24, 2020 · PreprintBioengineering