Author

J. Pallesen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:cryo-EM· 2 Organism:chicken / avian· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. B. Ward· 4 shared C. A. Cottrell· 2 shared H. L. Turner· 2 shared I. A. Wilson· 2 shared A. E. Dubin· 1 shared A. Moore· 1 shared A. Newman· 1 shared A. Patapoutian· 1 shared

Activity by Year

2018-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersImmunology

A. B. Ward

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drive rapid and potent immunogenicity capable of single-dose protection

K. Konrath, K. Liaw, Y. Wu, X. Zhu, S. Walker, Z. Xu, K. Schultheis, N. Chokkalingam, N. J. Tursi, J. Du, M. Sullivan, M. Purwar, A. Moore, V. Machado, I. Maricic, , D. W. Kulp

This study develops glycan-modified SARS-CoV-2 nanoparticle vaccines that induce potent neutralizing antibodies and single-dose protection against SARS-CoV-2 in multiple animal models.

bioRxiv · Apr 28, 2021Immunology

Chimpanzee SIV Envelope trimer: structure and deployment as an HIV vaccine template

R. Andrabi, J. Pallesen, J. Allen, G. Song, J. Zhang, N. de Val, G. Gegg, K. Porter, C.-Y. Su, M. Pauthner, A. Newman, H. Bouton-Vervelle, F. Garces, I. A. Wilson, M. Crispin, , D. R. Burton

The paper describes the structure of a chimpanzee SIV Env trimer and shows it induces HIV V2-specific neutralizing antibodies in mice.

bioRxiv · Nov 1, 2018Immunology

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor binding head domains

H. L. Turner, J. Pallesen, S. Lang, S. Bangaru, S. Urata, S. Li, C. A. Cottrell, C. A. Bowman, J. E. Crowe, I. A. Wilson, A. B. Ward

The paper identifies a transiently exposed epitope on influenza H7 hemagglutinin that is targeted by a potent neutralizing monoclonal antibody.

bioRxiv · Oct 5, 2018Immunology

Structure of the Human Volume Regulated Anion Channel

J. M. Kefauver, K. Saotome, A. E. Dubin, J. Pallesen, C. A. Cottrell, G. Hong, S. M. Cahalan, Z. Qiu, C. S. Crowley, T. Whitwam, W.-H. Lee, A. B. Ward, A. Patapoutian

The paper reports the high-resolution cryo-EM structure of human SWELL1, revealing its trimer of dimers assembly and identifying a charged residue critical for pore function in VRAC.

bioRxiv · May 16, 2018Biochemistry

Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

R. N. Kirchdoerfer, N. Wang, J. Pallesen, D. Wrapp, H. L. Turner, C. A. Cotrell, K. S. Corbett, B. S. Graham, J. S. McLellan, A. B. Ward

This study uses cryo-EM to show that ACE2 binding and trypsin cleavage of SARS-CoV spike protein do not cause major conformational changes or expose the S2 cleavage site.

bioRxiv · Mar 31, 2018Biochemistry