Author

A. Fujimoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 2 Biochemistry· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

A. Kitamura· 3 shared H. Nakagawa· 2 shared J. H. Wong· 2 shared M. Kinjo· 2 shared A. Koike· 1 shared A. Oku-Sasaki· 1 shared A. Ono· 1 shared C. Chen· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersBiophysics

A. Kitamura

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Stress granule dysfunction via chromophore-associated light inactivation

T. Koizumi, A. Fujimoto, H. Kawaguchi, T. Kurosaki, A. Kitamura

This study demonstrates that chromophore-associated light inactivation (CALI) can inactivate stress granules in live cells, affecting cell viability during recovery from hyperosmotic stress.

bioRxiv · Aug 12, 2023Biophysics

Short repeat RNA reduces cytotoxicity by preventing the aggregation of TDP-43 and its 25 kDa carboxy-terminal fragment

A. Fujimoto, M. Kinjo, A. Kitamura

The paper identifies short RNA repeats that reduce TDP-43 and TDP25 aggregation and cytotoxicity without altering the transcriptome.

bioRxiv · Jul 3, 2022 · PreprintBiochemistry

Interaction between spike protein of SARS-CoV-2 and human virus receptor ACE2 using two-color fluorescence cross-correlation spectroscopy

A. Fujimoto, Y. Lyu, M. Kinjo, A. Kitamura

This study uses two-color fluorescence cross-correlation spectroscopy to analyze the interaction between SARS-CoV-2 S1 subunit and human ACE2, showing stronger binding of SARS-CoV-2 compared to SARS-CoV and one-to-one stoichiometry.

bioRxiv · Aug 18, 2021Biophysics

Comprehensive analysis of full-length transcripts reveal aberrations of splicing variants in liver cancer

H. Kiyose, H. Nakagawa, A. Ono, H. Aikata, M. Ueno, S. Hayami, H. Yamaue, K. Chayama, M. Shimada, J. H. Wong, A. Fujimoto

The paper develops a pipeline to analyze full-length transcripts using long-read sequencing and identifies splicing variants and fusion events in liver cancer.

bioRxiv · Jun 28, 2021Cancer Biology

TGF-β inhibitor accelerates BMP4-induced cochlear gap junction formation during in vitro differentiation of embryonic stem cells

I. Fukunaga, C. Chen, Y. Oe, K. Danzaki, S. Ohta, A. Koike, A. Fujimoto, K. Ikeda, K. Kamiya

This study shows that the TGF-β inhibitor SB431542 accelerates BMP4-induced gap junction formation in CX26GJCs derived from mouse iPSCs, improving their yield for therapeutic applications.

bioRxiv · Feb 17, 2020Cell Biology

Dynamic rotation of the protruding domain enhances the infectivity of norovirus

C. Song, R. Takai-Todaka, M. Miki, K. Haga, A. Fujimoto, R. Ishiyama, K. Oikawa, M. Yokoyama, N. Miyazaki, K. Iwasaki, K. Murakami, K. Katayama, K. Murata

This study shows that the protruding domain of norovirus capsids dynamically rotates between rising and resting conformations in response to pH and metal ions, enhancing infection efficiency.

bioRxiv · Dec 16, 2019Pathology

Comprehensive Analysis of Indels in Whole-genome Microsatellite Regions and Microsatellite Instability across 21 Cancer Types

A. Fujimoto, M. Fujita, T. Hasegawa, K. Maejima, K. Nakano, A. Oku-Sasaki, J. H. Wong, Y. Shiraishi, S. Miyano, S. Imoto, M. R. Stratton, S. G. Rosen, H. Nakagawa

The paper analyzes microsatellite mutations across 21 cancer types, identifies MSI cancers, and finds factors influencing mutation rates and functional impacts.

bioRxiv · Feb 22, 2019Cancer Biology