Author

K. Nakano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

A. B. Behjat· 1 shared A. Fujimoto· 1 shared A. Kanatani· 1 shared A. Kumar· 1 shared A. Oku-Sasaki· 1 shared A. Yabuki· 1 shared A. Yurtsever· 1 shared C. Chantarasrivong· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

A. B. Behjat

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Author profile →

7 papers

Recent·Most cited

Impact of perinatal maternal docosahexaenoic acid-containing phospholipid synthesis on offspring growth and neurological symptoms

A. Kanatani, D. Hishikawa, K. Nagata, F. Hamano, K. Nakano, T. Okamura, T. Shimizu, H. Shindou, T. Nagamatsu, K. Yanagida

This study shows that maternal DHA-PL synthesis during fetal development affects offspring neuropsychiatric outcomes, but not postnatal growth or brain size.

bioRxiv · Jan 6, 2024 · PreprintBiochemistry

Heart generation via blastocyst complementation in Mesp1/2-deficient mice

Y. Abe, T. Sadahiro, R. Fujita, Y. Yamada, T. Akiyama, K. Nakano, S. Honda, Y. Tanimoto, H. Suzuki, S. Mizuno, S. Takahashi, T. Yamaguchi, H. Masaki, K. Hattori, T. Mashimo, M. Ieda

This study generates functional adult hearts in Mesp1/2-deficient mice using blastocyst complementation with pluripotent stem cells, showing successful derivation of all cardiovascular lineages from exogenous cells.

bioRxiv · Nov 8, 2023 · PreprintCell Biology

Encyclopaedia of family A DNA polymerases localized in organelles: Contribution of genes from bacteria including the proto-mitochondrion.

R. Harada, Y. Hirakawa, A. Yabuki, E. Kim, E. Yazaki, R. Kamikawa, K. Nakano, M. Elias, Y. Inagaki

This study identifies and classifies 134 family A DNA polymerase sequences from diverse eukaryotes, revealing their evolutionary origins and suggesting the last eukaryotic common ancestor had two mitochondrial DNAPs.

bioRxiv · Aug 28, 2023Evolutionary Biology

Actin binding domain of Rng2 sparsely bound on F-actin strongly inhibits actin movement on myosin II

Y. Hayakawa, M. Takaine, K. X. Ngo, T. Imai, M. Yamada, A. B. Behjat, K. Umeda, K. Hirose, A. Yurtsever, N. Kodera, K. Tokuraku, O. Numata, T. Fukuma, T. Ando, K. Nakano, T. Uyeda

The paper shows that the Rng2CHD domain inhibits actin filament motility on myosin II at low binding ratios, suggesting it modulates actin-myosin interactions through structural changes.

Life Science Alliance · Oct 26, 2022Peer-reviewedBiophysics

KSHV Topologically Associating Domains in Latent and Reactivated Viral Chromatin

M. Campbell, C. Chantarasrivong, Y. Yanagihashi, T. Inagaki, R. R. Davis, K. Nakano, A. Kumar, C. Tepper, Y. Izumiya

This paper reveals the 3D chromatin structure of KSHV during latency and reactivation, showing similar TAD organization and reorganization of regulatory units.

bioRxiv · Apr 5, 2022Microbiology

Comprehensive Analysis of Indels in Whole-genome Microsatellite Regions and Microsatellite Instability across 21 Cancer Types

A. Fujimoto, M. Fujita, T. Hasegawa, K. Maejima, K. Nakano, A. Oku-Sasaki, J. H. Wong, Y. Shiraishi, S. Miyano, S. Imoto, M. R. Stratton, S. G. Rosen, H. Nakagawa

The paper analyzes microsatellite mutations across 21 cancer types, identifies MSI cancers, and finds factors influencing mutation rates and functional impacts.

bioRxiv · Feb 22, 2019Cancer Biology

Identification of evolutionarily conserved virulence factor by selective pressure analysis of Streptococcus pneumoniae

M. Yamaguchi, K. Goto, Y. Hirose, Y. Yamaguchi, T. Sumitomo, M. Nakata, K. Nakano, S. Kawabata

The paper identifies a conserved virulence factor in Streptococcus pneumoniae through evolutionary analysis and shows its role in immune evasion.

bioRxiv · Dec 11, 2018Microbiology