Author

J. Claesen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:mouse· 5 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:metagenomics· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

J. M. Brown· 4 shared L. J. Osborn· 4 shared B. DeLucia· 3 shared C. McDonald· 2 shared D. Orabi· 2 shared I. Choucair· 2 shared K. B. Schultz· 2 shared K. Fung· 2 shared

Activity by Year

2019-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersMicrobiology

J. M. Brown

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A 3D printable device allowing fast and reproducible longitudinal preparation of mouse intestines

B. DeLucia, S. Samorezov, M. T. Zangara, R. L. Markley, L. J. Osborn, K. B. Schultz, C. McDonald, J. Claesen

The paper introduces a 3D printable tool for quickly and consistently dissecting mouse intestines, reducing preparation time and improving reproducibility compared to traditional methods.

bioRxiv · Dec 1, 2021Pathology

A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis

L. J. Osborn, K. Schultz, W. Massey, B. DeLucia, I. Choucair, V. Varadharajan, K. Fung, A. J. Horak, D. Orabi, I. Nemet, L. E. Nagy, Z. Wang, D. S. Allende, N. Sangwan, A. M. Hajjar, , J. Claesen

bioRxiv · Sep 16, 2021Microbiology

Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation

I. Johnston, L. J. Osborn, R. L. Markley, E. A. McManus, A. Kadam, K. B. Schultz, N. Nagajothi, P. A. Ahern, J. M. Brown, J. Claesen

This study identifies essential genes for aryl polyene biosynthesis in E. coli and shows APEs enhance biofilm formation and oxidative stress resistance.

npj Biofilms and Microbiomes · Jul 2, 2021Peer-reviewedMicrobiology

A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell wall acetylation

M. Özcam, J.-H. Oh, R. Tocmo, D. Acharya, S. Zhang, T. Astmann, M. Heggen, S. Ruiz-Ramirez, F. Li, C. C. Cheng, E. Vivas, F. E. Rey, J. Claesen, T. Bugni, J. Walter, J. P. van Pijkeren

The study identifies a secondary metabolite produced by L. reuteri that mediates intraspecies antagonism, with resistance linked to cell wall acetylation.

bioRxiv · Jun 11, 2021Microbiology

A Novel Surgical Method for Continuous Intra-Portal Infusion of Gut Microbial Metabolites in Mice

D. Orabi, L. J. Osborn, K. Fung, F. Aucejo, I. Choucair, B. DeLucia, Z. Wang, J. Claesen, J. M. Brown

This paper introduces a novel surgical method for continuous portal vein infusion of gut microbial metabolites in mice, demonstrating its effectiveness in altering plasma and hepatic metabolite levels and gene expression.

bioRxiv · Oct 29, 2020Microbiology

Disruption of the gut microbiota attenuates epithelial ovarian cancer sensitivity to cisplatin therapy

L. Chambers, E. L. Esakov, C. Braley, L. Trestan, Z. Alali, D. Bayik, J. Lathia, N. Sangwan, P. Bazeley, A. S. Joehlin-Price, M. Dwidar, A. Hajjar, P. P. Ahern, J. Claesen, P. Rose, , O. Reizes

This study shows that antibiotic treatment disrupts the gut microbiome, leading to increased resistance to cisplatin in ovarian cancer models.

bioRxiv · Jun 16, 2020 · PreprintCancer Biology

Cutibacterium acnes antibiotic production shapes niche competition in the human skin microbiome

J. Claesen, J. B. Spagnolo, S. Flores Ramos, K. L. Kurita, A. L. Byrd, A. A. Aksenov, A. V. Melnik, W. R. Wong, S. Wang, R. D. Hernandez, M. S. Donia, P. C. Dorrestein, H. H. Kong, J. A. Segre, R. G. Linington, , K. P. Lemon

The paper identifies cutimycin, an antibiotic produced by Cutibacterium acnes, which reduces Staphylococcus colonization in human skin follicles.

bioRxiv · Mar 30, 2019Microbiology