Nanobody Mediated Macromolecular Crowding Induces Membrane Fission and Remodeling in the African Trypanosome
A. Hempelmann, L. Hartleb, M. Van Straaten, H. Hashemi, J. P. Zeelen, F. N. Papavasiliou, M. Engstler, C. E. Stebbins, N. G. Jones
The paper shows that nanobodies induce membrane fission and remodeling in African trypanosomes by causing macromolecular crowding, leading to loss of motility and nanovesicle shedding.
bioRxiv · Jan 13, 2021Microbiology