Author

D. A. Moore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

T. Marafioti· 3 shared A. Huebner· 2 shared A. U. Akarca· 2 shared C. Swanton· 2 shared D. R. Pearce· 2 shared M. Sivakumar· 2 shared R. E. Hynds· 2 shared S. M. Janes· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

T. Marafioti

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer

D. R. Pearce, A. U. Akarca, R. P. H. De Maeyer, E. Kostina, A. Huebner, M. Sivakumar, T. Karasaki, K. Shah, S. M. Janes, N. E. McGranahan, V. Reddy, A. Akbar, D. A. Moore, T. Marafioti, C. Swanton, R. E. Hynds

The paper identifies lymphoproliferative B cells in NSCLC PDX models and develops a tool for generating pathology overview figures.

bioRxiv · Jan 24, 2023Cancer Biology

Genomic evolution of non-small cell lung cancer patient-derived xenograft models

R. E. Hynds, A. Huebner, D. R. Pearce, A. U. Akarca, D. A. Moore, S. Ward, K. H. C. Gowers, T. Karasaki, M. S. Hill, M. Al Bakir, G. A. Wilson, O. Pich, M. Sivakumar, A. Ben Aissa, E. Gronroos, , C. Swanton

This study examines how well PDX models capture intratumour heterogeneity in NSCLC, finding that most models originate from a single subclone but regional models can capture diversity.

bioRxiv · Jan 6, 2023Cancer Biology

Exaggerated in vivo IL-17 responses discriminate recall responses in active TB

G. Pollara, C. T. Turner, G. S. Tomlinson, L. C. Bell, A. Khan, L. F. Peralta, A. Folino, A. Akarca, C. Venturini, T. Baker, F. L. Ricciardolo, T. Marafioti, C. Ugarte-Gil, D. A. Moore, B. M. Chain, M. Noursadeghi

The paper shows that exaggerated IL-17A/F responses in active TB distinguish it from cured or latent TB, suggesting therapeutic targeting of this pathway.

bioRxiv · Jul 31, 2020Immunology

Host transcriptional response to TB preventive therapy differentiates two sub-groups of IGRA-positive individuals

C. Broderick, J. M. Cliff, J.-S. Lee, M. Kaforou, D. A. Moore

The paper analyzes transcriptional responses to tuberculosis preventive therapy in IGRA-positive individuals, identifying two subgroups with distinct gene expression patterns linked to Mtb viability.

bioRxiv · Jul 20, 2020Immunology

Overprecision Increases Subsequent Surprise

D. Schatz, D. A. Moore

This study examines how confidence affects surprise after feedback, finding that higher confidence reduces surprise for correct answers but not for incorrect ones, highlighting issues with confidence-interval measures.

bioRxiv · Dec 13, 2019Animal Behavior & Cognition