Author

D. A. Cantrell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 6

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 6 Approach:experimental assay· 6 Organism:mouse· 5 Assay:proteomics· 4 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:protein folding & dynamics· 2

Frequent Co-Authors

J. M. Marchingo· 4 shared L. Spinelli· 4 shared A. J. Howden· 3 shared J. L. Hukelmann· 3 shared L. V. Sinclair· 3 shared A. I. Lamond· 2 shared A. J. Brenes· 2 shared A. Casey· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

J. M. Marchingo

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

PIM kinase control of CD8 T cell protein synthesis and cell trafficking

J. M. Marchingo, L. Spinelli, S. Pathak, D. A. Cantrell

This study shows PIM kinases selectively regulate IL-2-driven protein synthesis and trafficking in CD8 T cells, without major effects on transcriptional programs.

bioRxiv · Mar 25, 2024Immunology

The Immunological Proteome Resource

A. J. Brenes, J. L. Hukelmann, L. Spinelli, A. J. M. Howden, J. M. Marchingo, L. V. Sinclair, C. Rollings, O. J. James, I. R. Phair, S. P. Matthews, S. H. Ross, S. C. Arthur, M. Swamy, D. K. Finlay, A. I. I. Lamond, D. A. Cantrell

The paper introduces ImmPRes, a proteomic resource integrating mass-spectrometry data from murine hematopoietic cells to study immune activation and signaling.

bioRxiv · Aug 29, 2022Immunology

Nrf2 is a central regulator of the metabolic landscape in macrophages and finetunes their inflammatory response

D. G. Ryan, E. V. Knatko, A. Casey, J. L. Hukelmann, A. J. Brenes, S. Dayalan Naidu, M. Higgins, L. Tronci, E. Nikitopoulou, L. A. O'Neill, A. I. Lamond, A. Y. Abramov, D. A. Cantrell, M. P. Murphy, A. T. Dinkova-Kostova

This study shows Nrf2 regulates macrophage metabolism, redox balance, and inflammatory responses, with 4-OI modulating these effects through Nrf2.

bioRxiv · Aug 13, 2021 · PreprintImmunology

Extracellular signal-regulated kinase (ERK) pathway control of CD8+ T cell differentiation

M. P. Damasio, J. M. Marchingo, L. Spinelli, D. A. Cantrell, A. J. Howden

This study uses mass spectrometry to identify ERK-regulated proteins in CD8+ T cells and reveals their role in transcriptional reprogramming and cytokine expression during activation.

bioRxiv · Aug 18, 2020Immunology

Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

J. M. Marchingo, L. V. Sinclair, A. J. Howden, D. A. Cantrell

This study uses mass spectrometry to show Myc controls T cell proteomes and metabolic pathways by regulating amino acid transporters, which are critical for T cell activation and function.

bioRxiv · Nov 18, 2019Immunology

Antigen receptor control of methionine metabolism in T cells

L. V. Sinclair, A. J. Howden, A. J. Brenes-Murillo, L. Spinelli, J. L. Hukelmann, A. N. Macintyre, X. Liu, S. Thomson, P. M. Taylor, J. C. Rathmell, J. W. Locasale, A. I. Lamond, D. A. Cantrell

This study shows antigen receptor engagement controls methionine cycle flux and methyl donor availability for RNA and histone methylation in T cells.

bioRxiv · Dec 18, 2018Immunology