Antigen receptor control of methionine metabolism in T cells
L. V. Sinclair, A. J. Howden, A. J. Brenes-Murillo, L. Spinelli, J. L. Hukelmann, A. N. Macintyre, X. Liu, S. Thomson, P. M. Taylor, J. C. Rathmell, J. W. Locasale, A. I. Lamond, D. A. Cantrell
This study shows antigen receptor engagement controls methionine cycle flux and methyl donor availability for RNA and histone methylation in T cells.
bioRxiv · Dec 18, 2018Immunology