Author

J. E. D. Thaventhiran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:GWAS / association mapping· 1 Organism:human· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. I. Jodrell· 2 shared K. Williamson· 2 shared P. A. Lyons· 2 shared A. Dannhorn· 1 shared A. G. Lynch· 1 shared A. G. Schuller· 1 shared A. J. Cutler· 1 shared A. Sanchis-Juan· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

D. I. Jodrell

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Fate-mapping lymphocyte clones and their progenies from induced antigen-signals identifies temporospatial behaviours of T cells mediating tolerance

M. Takahashi, T. So, K. Williamson, Z. Hosseini, K. Kania, M. Ruhle, T. Mann, M. J. Schujis, P. Coupland, D. Naisbitt, T. Y. F. Halim, P. A. Lyons, P. Lio, K. Okkenhaug, D. J. Adams, , J. E. D. Thaventhiran

This study introduces a novel fate-mapping mouse to track lymphocyte clones and their progenies in response to antigen signals, revealing distinct T cell behaviors in tumor immunity.

bioRxiv · Mar 16, 2023Immunology

Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma

V. Graziano, A. Dannhorn, H. Hulme, K. Williamson, H. Buckley, S. A. Karim, S. Y. Lee, B. P. Kaistha, S. Islam, J. E. D. Thaventhiran, F. M. Richards, R. Goodwin, R. Brais, J. P. Morton, S. J. Dovedi, , D. I. Jodrell

This study shows that extracellular adenosine promotes an immunosuppressive microenvironment in PDAC by enhancing myeloid cell infiltration and resistance to immunotherapy, and that blocking adenosine pathway components improves therapeutic outcomes.

bioRxiv · May 24, 2022Cancer Biology

Whole-genome sequencing of a sporadic primary immunodeficiency cohort

J. E. D. Thaventhiran, H. Lango Allen, O. S. Burren, W. Rae, D. Greene, E. Staples, Z. Zhang, J. H. R. Farmery, I. Simeoni, J. Maimaris, C. Penkett, J. Stephens, S. V. V. Deevi, A. Sanchis-Juan, N. S. Gleadall, , Kuma

This study uses whole-genome sequencing of a PID cohort to identify genetic mutations and associations, revealing both monogenic and common variant contributions to immune dysfunction.

bioRxiv · May 7, 2020Immunology