Author

A. K. Chopra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Organism:Arabidopsis· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:genetic perturbation / CRISPR· 1 Organism:rat· 1

Frequent Co-Authors

J. Sha· 4 shared P. B. Kilgore· 4 shared E. Hendrix· 3 shared A. Drelich· 2 shared H. Batra· 2 shared J. Zhu· 2 shared N. Ananthaswamy· 2 shared S. Jain· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

J. Sha

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Bacteriophage Cocktail Targeting Yersinia pestis Provides Strong Post-Exposure Protection in a Rat Pneumonic Plague Model

P. B. Kilgore, J. Sha, E. Hendrix, B. H. Neil, W. S. Lawrence, J. Peel, L. Hittle, J. Woolston, A. Sulakvelidze, J. Schwartz, A. K. Chopra

This paper evaluates a bacteriophage cocktail, YPP-401, for post-exposure protection against pneumonic plague in rats, showing ~88% protection when administered intranasally or intraperitoneally 18 hours post-exposure.

bioRxiv · Jan 17, 2024 · PreprintMicrobiology

A bacteriophage-based, highly efficacious, needle and adjuvant-free, mucosal COVID-19 vaccine

J. Zhu, S. Jain, J. Sha, H. Batra, N. Ananthaswamy, P. B. Kilgore, E. Hendrix, Y. M. Hosakote, X. Wu, J. P. Olano, A. Kayode, C. L. Galindo, S. Banga, A. Drelich, V. Tat, , V. B. Rao

This paper develops a bacteriophage-based mucosal vaccine that induces strong immune responses and protects against SARS-CoV-2 and its variants without requiring needles or adjuvants.

bioRxiv · Apr 28, 2022Microbiology

Combinatorial viral vector-based and live-attenuated vaccines without an adjuvant to generate broader immune responses to effectively combat pneumonic plague

P. B. Kilgore, J. Sha, E. Hendrix, V. L. Motin, A. K. Chopra

This study evaluates a combination of adenovirus vector and live-attenuated vaccines for pneumonic plague, showing that a two-dose regimen provides full protection against multiple challenges.

bioRxiv · Oct 28, 2021Microbiology

A Universal Bacteriophage T4 Nanoparticle Platform to Design Multiplex SARS-CoV-2 Vaccine Candidates by CRISPR Engineering

V. B. Rao, J. Zhu, N. Ananthaswamy, S. Jain, H. Batra, W.-C. Tang, D. A. Lewry, M. L. Richards, S. A. David, P. B. Kilgore, J. Sha, A. Drelich, C.-T. Tseng, A. K. Chopra

This paper develops a CRISPR-engineered bacteriophage T4 nanoparticle platform to create multiplex SARS-CoV-2 vaccine candidates, showing potent immune responses and protection in animal models.

bioRxiv · Jan 19, 2021Microbiology

Gut-associated bacteria invade the midgut epithelium of Aedes aegypti and stimulate innate immunity and suppress Zika virus infection in cells.

S. Hegde, D. Voronin, A. Casas-Sanchez, M. A. Saldana, E. Heinz, A. Acosta-Serrano, V. L. Popov, A. K. Chopra, G. L. Hughes

This study shows gut bacteria invade mosquito cells, activate immune pathways, and reduce Zika virus infection.

bioRxiv · Jan 16, 2020 · PreprintMicrobiology