Author

T. Thompson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Cort· 1 shared A. Hagg· 1 shared A. K. Ghosh· 1 shared A. K. Tripathi· 1 shared A. M. Edwards· 1 shared A. T. Raman· 1 shared B. Hristov· 1 shared C. A. Harrison· 1 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Cort

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Deciphering the non-coding code of pathogenicity and sexual differentiation in the human malaria parasite.

G. Batugedara, X. M. Lu, S. Abel, Z. Chahine, B. Hristov, D. Williams, T. Hollin, T. Wang, A. Cort, T. Lenz, T. Thompson, J. Prudhomme, A. K. Tripathi, G. Xu, J. Cudini, , K. G. Le Roch

This study identifies and characterizes long non-coding RNAs (lncRNAs) in Plasmodium falciparum, revealing their role in gene regulation, pathogenicity, and sexual differentiation.

bioRxiv · Oct 12, 2022 · PreprintMicrobiology

An open source plant kinase chemogenomics set

M. F. Ercoli, P. Zonzini Ramos, R. Jain, J. Pilotte, O. X. Dong, T. Thompson, C. I. Wells, J. M. Elkins, A. M. Edwards, R. M. Counago, D. H. Drewry, P. C. Ronald

The paper presents a plant kinase chemogenomics set, identifying compounds that affect root development in Arabidopsis and rice, with implications for understanding plant kinase function.

bioRxiv · Jun 18, 2022Plant Biology

The orphan ligand, Activin C, signals through activin receptor-like kinase 7

E. J. Goebel, L. Ongaro, E. C. Kappes, E. Belcheva, R. Castonguay, R. Kumar, D. J. Bernard, T. Thompson

This study characterizes the signaling properties of Activin C and its heterodimer ActAC, showing they activate SMAD2/3 via ALK7 with distinct receptor and antagonist profiles compared to ActA and ActB.

bioRxiv · Mar 16, 2022Biochemistry

H3K4me1-marked Enhancer Activation in Resistant Prostate Cancers Implicates SOX4 and MENIN Inhibition as Therapeutic Strategies

C. Terranova, M. Maitituoheti, A. T. Raman, M. Tang, N. E. Anvar, A. K. Ghosh, S. B. Amin, J. Schulz, E. Orouji, F. Giancotti, P. Troncoso, C. J. Logothetis, T. Thompson, K. Rai

The paper identifies H3K4me1-marked enhancers in therapy-resistant prostate cancers and suggests SOX4 and MENIN inhibition as therapeutic strategies.

bioRxiv · Sep 2, 2021 · PreprintCancer Biology

Molecular characterization of latent GDF8 reveals mechanisms of activation

R. G. Walker, J. C. McCoy, M. Czepnik, M. J. Mills, A. Hagg, K. L. Walton, T. Cotton, M. Hyvonen, R. T. Lee, P. Gregorevic, C. A. Harrison, T. Thompson

This study characterizes the latent and activated states of GDF8 using structural and mutagenesis analyses, revealing that latent GDF8 is spring-loaded and can be activated without proteolytic cleavage.

bioRxiv · Aug 17, 2017Biochemistry