Author

A. Kalita

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:E. coli· 2 Assay:metabolomics· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. Dutta· 3 shared R. K. Mishra· 3 shared A. Arora· 2 shared A. Prakash· 2 shared D. Ghose· 2 shared E. E. Hesles· 2 shared J. S. Smith· 2 shared V. Kumar· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiochemistry

D. Dutta

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Rho and a riboswitch regulate mntP expression evading manganese stress and membrane toxicity

A. Prakash, A. Kalita, K. Bhardwaj, R. K. Mishra, D. Ghose, G. Kaur, B. Pani, E. Nudler, D. Dutta

The paper shows Rho terminates transcription at the mntP riboswitch, and manganese activates the riboswitch to restore transcription-translation coupling, preventing membrane toxicity from overexpressed MntP.

bioRxiv · Nov 29, 2023 · PreprintBiochemistry

An intrinsic alkalization circuit turns on mntP-riboswitch under manganese stress in Escherichia coli

A. Kalita, R. K. Mishra, V. Kumar, A. Arora, D. Dutta

The paper shows that manganese stress in E. coli activates a circuit involving ammonia production and cytoplasmic alkalization, enhancing mntP-riboswitch activation to improve manganese tolerance.

bioRxiv · Aug 31, 2022Biochemistry

Free spermidine evokes superoxide radicals that manifest toxicity

V. Kumar, R. K. Mishra, D. Ghose, A. Kalita, A. Prakash, G. Mitra, A. Arora, D. Dutta

The paper shows that excess free spermidine generates superoxide radicals, causing toxicity in bacteria lacking the SpeG enzyme, while SpeG enables tolerance by neutralizing spermidine.

bioRxiv · Sep 4, 2021Biochemistry

Chronological lifespan extension and nucleotide salvage inhibition in yeast by isonicotinamide supplementation

A. Kalita, C. T. Letai, E. E. Hesles, L. N. Power, S. Mishra, S. Saha, M. Dinda, D. Wang, P. K. Singh, J. S. Smith

This study shows that isonicotinamide (INAM) extends yeast chronological lifespan by inhibiting nucleotide salvage pathways, leading to NAD+ accumulation and a hormetic stress response.

bioRxiv · Jul 11, 2021Biochemistry

A cell non-autonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism

E. E. Hesles, D. L. Smith, N. S. Maqani, M. B. Wierman, M. D. Sutcliffe, R. D. Fine, A. Kalita, S. M. Santos, M. J. Muehlbauer, J. R. Bain, K. A. Janes, J. L. Hartman, M. D. Hirschey, J. S. Smith

bioRxiv · Jul 13, 2020Cell Biology