Author

A. Kay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Research Focus:development & morphogenesis· 1 Assay:proteomics· 1

Frequent Co-Authors

A. M. Mandalakas· 2 shared A. R. DiNardo· 2 shared C. Coarfa· 2 shared G. Makedonas· 2 shared G. Maphalala· 2 shared G. Mtetwa· 2 shared K. Rajapakshe· 2 shared T. Nishiguchi· 2 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

A. M. Mandalakas

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Persistent DNA Hyper-methylation Dampens Host Anti-Mycobacterial Immunity

A. R. DiNardo, K. Rajapakshe, T. Nishiguchi, G. Mtetwa, Q. Dlamini, J. Kahari, S. Mahapatra, A. Kay, G. Maphalala, E. Mace, S. L. Grimm, G. Makedonas, J. D. Cirillo, M. G. Netea, R. van Crevel, , A. M. Mandalakas

This study identifies DNA hyper-methylation in immune-related pathways of TB patients, leading to reduced immune responsiveness to mycobacterial antigens.

bioRxiv · Oct 16, 2019 · PreprintImmunology

CD38 contributes to human natural killer cell responses through a role in immune synapse formation

M. Le Gars, C. Seiler, A. Kay, N. Bayless, E. Sola, E. Starosvetsky, L. Moore, S. Shen-Orr, N. Aziz, C. Dekker, P. Khatri, G. Swan, M. Davis, S. Holmes, C. Blish

This study identifies CD38 as a key receptor in human NK cells that facilitates immune synapse formation, enhancing antiviral and antitumor responses.

bioRxiv · May 24, 2019 · PreprintImmunology

Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-specific Immune Changes

A. R. DiNardo, T. Nishiguchi, E. M. Mace, K. Rajapakshe, G. Mtetwa, A. Kay, G. Maphalala, W. E. Secor, R. A. Mejia, C. Coarfa, K. N. Bhalla, E. A. Graviss, J. S. Orange, G. Makedonas, A. M. Mandalakas

This study shows helminth infections cause long-term DNA methylation and immune changes that impair TB-specific immune responses.

bioRxiv · Jan 27, 2018Immunology

Decoupled Maternal and Zygotic Genetic Effects Shape the Evolution of Development

C. Zakas, J. Deutscher, A. Kay, M. Rockman

The paper identifies maternal and zygotic genetic effects shaping larval development in Streblospio benedicti, showing epistasis between these effects influences fitness.

bioRxiv · Oct 10, 2017Evolutionary Biology