Author

A. M. Dinan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

G. M. Cook· 2 shared H. Stewart· 2 shared I. Brierley· 2 shared K. Brown· 2 shared N. Irigoyen· 2 shared R. A. Floto· 2 shared A. E. Firth· 1 shared A. Firth· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

G. M. Cook

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Sequence-based modelling of bacterial genomes enables accurate antibiotic resistance prediction

M. Wiatrak, A. Weimann, A. M. Dinan, M. Brbic, R. A. Floto

This study introduces GeneBac, a deep learning model that predicts antibiotic resistance from bacterial genomic sequences, showing accurate MIC prediction and variant effect assessment.

bioRxiv · Jan 3, 2024 · PreprintMicrobiology

Zika viruses encode multiple upstream open reading frames in the 5' viral region with a role in neurotropism

C. Lefevre, G. M. Cook, A. M. Dinan, S. Torii, H. Stewart, G. Gibbons, A. S. Nicholson, L. Echavarria-Consuegra, L. W. Meredith, V. Lulla, J. C. Kenyon, I. G. Goodfellow, J. E. Deane, S. C. Graham, A. Lakatos, , N. Irigoyen

This study identifies multiple upstream open reading frames (uORFs) in Zika virus (ZIKV) that influence neurotropism but not mosquito transmission.

bioRxiv · Apr 20, 2023 · PreprintMicrobiology

Epigenetic and transcriptional plasticity drive inflammation in Cystic Fibrosis

A. M. Dinan, O. Eneje, K. P. Brown, F. Burden, M. Morse, R. Prinjha, M. Frontini, R. A. Floto

The paper links acute pulmonary exacerbations in Cystic Fibrosis to immune signaling and epigenetic changes, showing antibiotic treatment reverses these effects.

bioRxiv · Oct 12, 2022 · PreprintImmunology

Ribosome profiling of porcine reproductive and respiratory syndrome virus reveals novel features of viral gene expression

G. M. Cook, K. Brown, P. Shang, Y. Li, L. Soday, A. M. Dinan, C. Tumescheit, A. P. A. Mockett, Y. Fang, A. E. Firth, I. Brierley

This study uses ribosome profiling to analyze PRRSV gene expression and reveals temporally regulated frameshifting and novel transcripts.

bioRxiv · Nov 17, 2021Pathology

The transcriptional and translational landscape of equine torovirus

H. Stewart, K. Brown, A. M. Dinan, N. Irigoyen, E. J. Snijder, A. Firth

This study analyzes the transcription and translation of equine torovirus using RNA-seq and Ribo-seq, identifying novel open reading frames and subgenomic RNA synthesis mechanisms.

bioRxiv · Apr 7, 2018Microbiology