Author

A. Mancini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

A. M. Amen· 1 shared A. M. McKinney· 1 shared A. S. Hauser· 1 shared B. Breton· 1 shared C. Avet· 1 shared C. Fellmann· 1 shared C. Le Gouill· 1 shared C. Normand· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. M. Amen

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage

A. M. Amen, C. Fellmann, K. M. Soczek, S. M. Ren, R. J. Lew, G. J. Knott, J. E. Park, A. M. McKinney, A. Mancini, J. A. Doudna, J. F. Costello

This study shows that reducing GABPB1L in TERT-mutant glioblastomas, combined with chemotherapy, reduces tumor growth by impairing DNA damage response.

Proceedings of the National Academy of Sciences · Mar 23, 2021Peer-reviewedCancer Biology

Effector membrane translocation biosensors reveal G protein and β-arrestin coupling profiles of 100 therapeutically relevant GPCRs

C. Avet, A. Mancini, B. Breton, C. Le Gouill, A. S. Hauser, C. Normand, H. Kobayashi, F. Gross, M. Hogue, V. Lukasheva, S. St-Onge, M. Carrier, M. Heroux, S. Morissette, E. Fauman, , M. Bouvier

The paper develops EMTA biosensors to profile G protein and β-arrestin coupling of 100 GPCRs, revealing diverse signaling profiles and drug-target interactions.

bioRxiv · Apr 20, 2020Pharmacology & Toxicology