Author

A. Norris

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Biochemistry· 3 Immunology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Assay:proteomics· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 3 Approach:statistical model· 3 Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

A. La Greca· 2 shared A. Lombardi· 2 shared B. D. Grant· 2 shared D. A. Myers· 2 shared J. F. Papin· 2 shared K. Singleton· 2 shared M. Maxted· 2 shared S. G. Miriuka· 2 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCell Biology

A. La Greca

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Author profile →

11 papers

Recent·Most cited

A Conserved Requirement for RME-8/DNAJC13 in Neuronal Autolysosome Reformation

S. B. Swords, N. Jia, A. Norris, J. Modi, Q. Cai, B. D. Grant

This study identifies RME-8/DNAJC13 as a conserved factor required for autolysosome reformation in neurons, linking it to autophagic flux and neurodegenerative disease mechanisms.

bioRxiv · Feb 27, 2023 · PreprintCell Biology

Syndapin and GTPase RAP-1 Control Endocytic Recycling via RHO-1 and Non-Muscle Myosin II

W. R. Rodriguez-Polanco, A. Norris, A. B. Velasco, A. Gleason, B. Grant

This study identifies SDPN-1 and RAP-1 as regulators of endocytic recycling in C. elegans, showing their interaction with RHO-1 and non-muscle myosin II.

bioRxiv · Feb 27, 2023 · PreprintCell Biology

Mutagenesis and structural modeling implicate RME-8 IWN domains as conformational control points

A. Norris, C. McManus, R. Ying, S. Wang, B. D. Grant

The paper identifies IWN domains in RME-8 as conformational control points that regulate DNAJ domain exposure and function through interactions with SNX-1.

PLOS Genetics · Oct 24, 2022Peer-reviewedCell Biology

Structure of a Rad52 homolog from bacteriophage in complex with a novel duplex intermediate of DNA annealing

B. J. Caldwell, A. Norris, V. H. Wysocki, C. E. Bell

This paper determines the structure of a bacteriophage RecT homolog bound to a novel DNA duplex intermediate, revealing insights into DNA annealing mechanisms.

bioRxiv · Mar 17, 2022 · PreprintBiochemistry

EARLY AND MID-GESTATION ZIKA VIRUS (ZIKV) INFECTION IN THE OLIVE BABOON (PAPIO ANUBIS) LEADS TO FETAL CNS PATHOLOGY BY TERM GESTATION

S. Gurung, D. Reuter, A. Norris, M. Dubois, M. Maxted, K. Singleton, M. Castillo-Castrejon, J. F. Papin, D. A. Myers

This study examines ZIKV infection in Olive baboons during early and mid-gestation, finding fetal CNS pathology by term gestation despite resolved viremia.

bioRxiv · Feb 23, 2022Pathology

Small extracellular vesicles from iPSC-MSC lose their regenerative potential upon UV-C irradiation

M. C. Biani, A. Lombardi, A. Norris, P. Bucci, A. La Greca, A. Waisman, L. N. Moro, G. Sevlever, J. Montanari, S. G. Miriuka, C. Luzzani

This study shows that UV-C irradiation of iPSC-MSC alters the cargo of secreted small EVs, reducing their ability to promote cell migration.

bioRxiv · Sep 27, 2021 · PreprintCell Biology

Effects of bacterial lipopolysaccharide and Shiga Toxin on induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells

D. Martire-Greco, A. La Greca, L. Castillo Montanez, C. Biani, A. Lombardi, F. Birnberg-Weiss, A. Norris, F. Sacerdoti, M. M. Amaral, N. Rodrigues-Rodriguez, J. R. Pittaluga, V. A. Furmento, V. I. Landoni, S. G. Miriuka, C. D. Luzzani, G. C. Fernandez

This study examines how LPS and Stx affect iPSC-MSC and their ability to repair endothelial damage, showing LPS induces inflammation while LPS+Stx impairs repair.

bioRxiv · Sep 7, 2021Immunology

Unloxing the assembly and activation mechanism of Cre recombinase using Cryo-EM

K. Stachowski, A. Norris, D. Potter, V. Wysocki, M. Foster

This paper determines cryo-EM structures of Cre-loxP assembly intermediates to elucidate mechanisms of site selection, strand cleavage order, and activation in the Cre recombinase system.

bioRxiv · Jul 31, 2021Biochemistry

MATERNAL ZIKA VIRUS (ZIKV) INFECTION FOLLOWING VAGINAL INOCULATION WITH ZIKV-INFECTED SEMEN IN THE TIMED-PREGNANT OLIVE BABOON

S. Gurung, H. Nadeau, M. Maxted, J. Peregrine, D. N. Reuter, A. Norris, R. K. Edwards, K. Hyatt, K. Singleton, J. F. Papin, D. A. Myers

This study infects pregnant olive baboons with ZIKV-infected semen via vaginal deposition, showing maternal infection and vertical transmission, with differences in tissue dissemination between ZIKV isolates.

bioRxiv · Jan 10, 2020Physiology

Cellular contractility coordinates cytoskeletal dynamics and cell behaviour during Drosophila abdominal morphogenesis

P. Pulido Companys, A. Norris, M. Bischoff

The paper investigates how cellular contractility coordinates cytoskeletal dynamics and cell behavior during Drosophila abdominal morphogenesis, finding that contractility levels and pulsatile actomyosin networks drive transitions between migration and constriction.

bioRxiv · Jun 28, 2019 · PreprintCell Biology

Reporter Ion Data Analysis Reduction (R.I.D.A.R) for isobaric proteomics quantification studies

C. Jenkins, A. Norris, M. O'Neill, S. Das, T. Andresson, B. Orsburn

The paper introduces RIDAR, a method to reduce computational load in isobaric proteomics by filtering MS/MS spectra before database searching, achieving an 85% time reduction on a standard desktop.

bioRxiv · Oct 7, 2018 · PreprintBiochemistry